CHICK:XRCC6

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	XRCC6 (synonyms: G22P1, KU70)
Protein Name(s)	X-ray repair cross-complementing protein 5 5'-deoxyribose-5-phosphate lyase Ku70 5'-dRP/AP lyase Ku70 ATP-dependent DNA helicase 2 subunit 1 ATP-dependent DNA helicase II 70 kDa subunit DNA repair protein XRCC6 Ku autoantigen protein p70 homolog Ku70
External Links
UniProt	O93257
EMBL	AB016529
RefSeq	NP_990258.1
UniGene	Gga.26690
ProteinModelPortal	O93257
SMR	O93257
BioGrid	676041
STRING	9031.ENSGALP00000037185
PaxDb	O93257
PRIDE	O93257
GeneID	395767
KEGG	gga:395767
CTD	2547
eggNOG	NOG305318
HOGENOM	HOG000006588
HOVERGEN	HBG006236
InParanoid	O93257
KO	K10884
PhylomeDB	O93257
Reactome	REACT_115694
NextBio	20815835
PRO	PR:O93257
Proteomes	UP000000539
GO	GO:0005694 GO:0043564 GO:0070419 GO:0005654 GO:0051575 GO:0005524 GO:0004003 GO:0003684 GO:0042162 GO:0006310 GO:0006281 GO:0006302 GO:0006303 GO:0045892 GO:0000723 GO:0006351
Gene3D	1.10.1600.10 1.10.720.30 2.40.290.10 3.40.50.410 4.10.970.10
InterPro	IPR006165 IPR006164 IPR027388 IPR005160 IPR005161 IPR003034 IPR016194 IPR002035
PANTHER	PTHR12604:SF2
Pfam	PF02735 PF03730 PF03731 PF02037
PIRSF	PIRSF003033
SMART	SM00559 SM00513
SUPFAM	SSF100939 SSF53300
TIGRFAMs	TIGR00578
PROSITE	PS50800

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:1990904	ribonucleoprotein complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P13010	C		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P13010	F		Seeded From UniProt	complete
involved_in	GO:0071480	cellular response to gamma radiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12956	P		Seeded From UniProt	complete
part_of	GO:0070419	nonhomologous end joining complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12956	C		Seeded From UniProt	complete
enables	GO:0051575	5'-deoxyribose-5-phosphate lyase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12956	F		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12956	P		Seeded From UniProt	complete
part_of	GO:0043564	Ku70:Ku80 complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12956	C		Seeded From UniProt	complete
involved_in	GO:0006303	double-strand break repair via nonhomologous end joining	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12956	P		Seeded From UniProt	complete
involved_in	GO:0071481	cellular response to X-ray		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000288287 RGD:2643 RGD:3976	P		Seeded From UniProt	complete
involved_in	GO:0071480	cellular response to gamma radiation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0041627 PANTHER:PTN000288287 UniProtKB:P12956 UniProtKB:P13010	P		Seeded From UniProt	complete
part_of	GO:0043564	Ku70:Ku80 complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0011774 PANTHER:PTN000288287 SGD:S000004712 SGD:S000004897 UniProtKB:P12956 UniProtKB:P13010 dictyBase:DDB_G0286069 dictyBase:DDB_G0286303	C		Seeded From UniProt	complete
enables	GO:0042162	telomeric DNA binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000288287 PomBase:SPBC543.03c PomBase:SPCC126.02c SGD:S000004712 UniProtKB:P13010	F		Seeded From UniProt	complete
involved_in	GO:0006303	double-strand break repair via nonhomologous end joining		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0011774 FB:FBgn0041627 MGI:MGI:95606 PANTHER:PTN000288287 PomBase:SPBC543.03c PomBase:SPCC126.02c SGD:S000004712 SGD:S000004897 TAIR:locus:2023757 TAIR:locus:2035495 UniProtKB:P12956 UniProtKB:P13010 UniProtKB:Q4WI96 dictyBase:DDB_G0286303	P		Seeded From UniProt	complete
contributes_to	GO:0003690	double-stranded DNA binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95606 PANTHER:PTN000288287 RGD:2643 RGD:3976 TAIR:locus:2023757 TAIR:locus:2035495	F		Seeded From UniProt	complete
part_of	GO:0000784	nuclear chromosome, telomeric region		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000288287 PomBase:SPBC543.03c PomBase:SPCC126.02c SGD:S000004712 UniProtKB:P13010	C		Seeded From UniProt	complete
involved_in	GO:0000723	telomere maintenance		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0011774 FB:FBgn0041627 PANTHER:PTN000288287 PomBase:SPBC543.03c PomBase:SPCC126.02c SGD:S000004712 SGD:S000004897 TAIR:locus:2035495 UniProtKB:A0A1D8PF81 UniProtKB:Q7F1M0	P		Seeded From UniProt	complete
involved_in	GO:0032508	DNA duplex unwinding	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004003	P		Seeded From UniProt	complete
involved_in	GO:0000723	telomere maintenance	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006165	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005160 InterPro:IPR006164 InterPro:IPR006165	F		Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006165	F		Seeded From UniProt	complete
enables	GO:0004003	ATP-dependent DNA helicase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005160	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006165	C		Seeded From UniProt	complete
involved_in	GO:0006303	double-strand break repair via nonhomologous end joining	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005160 InterPro:IPR006164 InterPro:IPR006165	P		Seeded From UniProt	complete
enables	GO:0042162	telomeric DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006165	F		Seeded From UniProt	complete
part_of	GO:0043564	Ku70:Ku80 complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006165	C		Seeded From UniProt	complete
involved_in	GO:0006303	double-strand break repair via nonhomologous end joining	Reactome:R-GGA-353423	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-GGA-353313 Reactome:R-GGA-353298 Reactome:R-GGA-353283 Reactome:R-GGA-353226	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
enables	GO:0004386	helicase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0347	F		Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0233	P		Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0158 UniProtKB-SubCell:SL-0468	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	F		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0456	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
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References

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