Category:GO:0004420 ! hydroxymethylglutaryl-CoA reductase (NADPH) activity

id: GO:0004420

name: hydroxymethylglutaryl-CoA reductase (NADPH) activity
namespace: molecular_function
alt_id: GO:0042282
def: "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH." [PMID:29224355, RHEA:15989]
synonym: "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [EC:1.1.1.34]
synonym: "HMG-CoA reductase activity" BROAD [EC:1.1.1.34]
synonym: "hydroxymethylglutaryl-CoA reductase activity" RELATED []
xref: EC:1.1.1.34
xref: KEGG_REACTION:R02082
xref: MetaCyc:1.1.1.34-RXN
xref: RHEA:15989
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AmiGO <GOterm>GO:0004420</GOterm>
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