PSEMV:MVAA

Species (Taxon ID)	Pseudomonas mevalonii. (32044)
Gene Name(s)	mvaA
Protein Name(s)	3-hydroxy-3-methylglutaryl-coenzyme A reductase HMG-CoA reductase
External Links
UniProt	P13702
EMBL	M24015 M29727
PDB	1QAX 1QAY 1R31 1R7I 1T02 4I4B 4I56 4I64 4I6A 4I6W 4I6Y
PDBsum	1QAX 1QAY 1R31 1R7I 1T02 4I4B 4I56 4I64 4I6A 4I6W 4I6Y
ProteinModelPortal	P13702
SMR	P13702
BioCyc	MetaCyc:MONOMER-11829
SABIO-RK	P13702
UniPathway	UPA00257
EvolutionaryTrace	P13702
GO	GO:0050662 GO:0004420 GO:0042282 GO:0015936
Gene3D	3.30.70.420 3.90.770.10
InterPro	IPR002202 IPR004553 IPR023074 IPR023076 IPR009023 IPR009029
PANTHER	PTHR10572
Pfam	PF00368
SUPFAM	SSF55035 SSF56542
TIGRFAMs	TIGR00532
PROSITE	PS00066 PS00318 PS01192 PS50065

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
Contributes to	GO:0042282	hydroxymethylglutaryl-CoA reductase activity	PMID:2656635	ECO:0000314			F		mvaA codes for the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Figure 5 shows E.coli cells transformed with the plasmid containing mvaA and induced with IPTG. Assayed for HMG-CoA reductase activity. Cells induced with IPTG resulted in HMG-CoA reductase activity shown in lane 1.	complete CACAO 4858
enables	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002202 InterPro:IPR023074 InterPro:IPR023076	F		Seeded From UniProt	complete
involved_in	GO:0015936	coenzyme A metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002202 InterPro:IPR004553 InterPro:IPR009029	P		Seeded From UniProt	complete
enables	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004553 InterPro:IPR009029	F		Seeded From UniProt	complete
enables	GO:0050662	coenzyme binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002202 InterPro:IPR004553 InterPro:IPR009023 InterPro:IPR009029	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002202 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076	P		Seeded From UniProt	complete
enables	GO:0042282	hydroxymethylglutaryl-CoA reductase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.88	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
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