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Category:GO:0035243 ! protein-arginine omega-N symmetric methyltransferase activity
name: protein-arginine omega-N symmetric methyltransferase activity
namespace: molecular_function
def: "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues." [EC:2.1.1.320, PMID:14705965, RESID:AA0067, RESID:AA0069]
comment: Note that type II protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243'.
synonym: "protein arginine omega-N symmetric methylase activity" EXACT []
synonym: "protein arginine omega-N symmetric methyltransferase activity" EXACT []
synonym: "S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming)" RELATED [EC:2.1.1.320]
synonym: "type II PRMT activity" RELATED []
synonym: "type II protein arginine methyltransferase activity" RELATED []
xref: EC:2.1.1.320
xref: RESID:AA0067
xref: RESID:AA0069
xref: RHEA:48108
is_a: GO:0016274 ! protein-arginine N-methyltransferase activity
AmiGO
<GOterm>GO:0035243</GOterm>
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