MOUSE:ANM7

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Prmt7 (synonyms: Kiaa1933)
Protein Name(s)	Protein arginine N-methyltransferase 7 Histone-arginine N-methyltransferase PRMT7 [Myelin basic protein]-arginine N-methyltransferase PRMT7
External Links
UniProt	Q922X9
EMBL	AY673972 AK173304 AK154255 AK162376 CH466525 BC006705 BC057177
CCDS	CCDS22633.1
RefSeq	NP_663379.1
UniGene	Mm.251804 Mm.446217
PDB	4C4A
PDBsum	4C4A
ProteinModelPortal	Q922X9
SMR	Q922X9
BioGrid	229540
DIP	DIP-29210N
PhosphoSite	Q922X9
MaxQB	Q922X9
PaxDb	Q922X9
PRIDE	Q922X9
Ensembl	ENSMUST00000071592
GeneID	214572
KEGG	mmu:214572
UCSC	uc009nfu.1
CTD	54496
MGI	MGI:2384879
eggNOG	COG0500
GeneTree	ENSGT00530000063495
HOGENOM	HOG000033951
HOVERGEN	HBG018729
InParanoid	Q922X9
KO	K11438
OMA	FDFQQPV
OrthoDB	EOG74FF0J
PhylomeDB	Q922X9
TreeFam	TF315221
Reactome	REACT_244207
ChiTaRS	Prmt7
NextBio	374360
PRO	PR:Q922X9
Proteomes	UP000000589
Bgee	Q922X9
CleanEx	MM_PRMT7
ExpressionAtlas	Q922X9
Genevestigator	Q922X9
GO	GO:0005829 GO:0005730 GO:0005634 GO:0005886 GO:0016277 GO:0044020 GO:0008469 GO:0035242 GO:0035241 GO:0035243 GO:0043021 GO:0008757 GO:0030154 GO:0043046 GO:0034969 GO:0043985 GO:0016571 GO:0018216 GO:0019919 GO:0006349 GO:0006355 GO:0000387 GO:0006351
Gene3D	3.40.50.150
InterPro	IPR025799 IPR014644 IPR010456 IPR029063
PANTHER	PTHR11006
Pfam	PF06325
PIRSF	PIRSF036946
SUPFAM	SSF53335
PROSITE	PS51678

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0035241	protein-arginine omega-N monomethyltransferase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
involved_in	GO:0018216	peptidyl-arginine methylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	P	Seeded From UniProt	complete
involved_in	GO:0016571	histone methylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	P	Seeded From UniProt	complete
enables	GO:0016277	[myelin basic protein]-arginine N-methyltransferase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0008469	histone-arginine N-methyltransferase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0044020	histone methyltransferase activity (H4-R3 specific)	PMID:17048991^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0043046	DNA methylation involved in gamete generation	PMID:17048991^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity	PMID:17048991^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0034969	histone arginine methylation	PMID:17048991^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006349	regulation of gene expression by genetic imprinting	PMID:17048991^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	C	Seeded From UniProt	complete
involved_in	GO:0000387	spliceosomal snRNP assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9NVM4	P	Seeded From UniProt	complete
enables	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0037770 FB:FBgn0037834 MGI:MGI:107846 MGI:MGI:1913208 PANTHER:PTN000109455 RGD:62020 RGD:620413 SGD:S000000238 TAIR:locus:2010607 TAIR:locus:2077567 TAIR:locus:2154339 UniProtKB:Q7Q2B7 UniProtKB:Q96LA8 UniProtKB:Q99873 UniProtKB:Q9NR22 WB:WBGene00013766	F	Seeded From UniProt	complete
enables	GO:0035241	protein-arginine omega-N monomethyltransferase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000109694 UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
involved_in	GO:0034969	histone arginine methylation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1913208 MGI:MGI:2384879 PANTHER:PTN000109455 UniProtKB:Q582G4	P	Seeded From UniProt	complete
NOT\|involved_in	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000109455 PANTHER:PTN000109694	P	Seeded From UniProt	complete
enables	GO:0008469	histone-arginine N-methyltransferase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1316652 MGI:MGI:2139971 PANTHER:PTN000109455 RGD:62020 TAIR:locus:2010607 TAIR:locus:2077567 TAIR:locus:2154339 UniProtKB:C8V494 UniProtKB:C8VIM6 UniProtKB:Q86X55 UniProtKB:Q96LA8 UniProtKB:Q9NR22 UniProtKB:Q9NVM4 WB:WBGene00013766	F	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1913208 PANTHER:PTN000109455 UniProtKB:Q7Q2B7	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1913208 MGI:MGI:1919224 PANTHER:PTN000109455 RGD:62020 TAIR:locus:2010607 TAIR:locus:2051995 TAIR:locus:2082244 TAIR:locus:2134328 UniProtKB:P55345 UniProtKB:Q86X55 UniProtKB:Q9NVM4	C	Seeded From UniProt	complete
enables	GO:0043021	ribonucleoprotein complex binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0035241	protein-arginine omega-N monomethyltransferase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0018216	peptidyl-arginine methylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016571	histone methylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	P	Seeded From UniProt	complete
enables	GO:0016277	[myelin basic protein]-arginine N-methyltransferase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
enables	GO:0008469	histone-arginine N-methyltransferase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	F	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	C	Seeded From UniProt	complete
part_of	GO:0001650	fibrillar center	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000387	spliceosomal snRNP assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9NVM4	P	Seeded From UniProt	complete
involved_in	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0035243	P	Seeded From UniProt	complete
involved_in	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0035243	P	Seeded From UniProt	complete
involved_in	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0035243	P	Seeded From UniProt	complete
involved_in	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0035243	P	Seeded From UniProt	complete
involved_in	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0035242	P	Seeded From UniProt	complete
involved_in	GO:0035246	peptidyl-arginine N-methylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0016277	P	Seeded From UniProt	complete
involved_in	GO:0035246	peptidyl-arginine N-methylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0016277	P	Seeded From UniProt	complete
involved_in	GO:0035246	peptidyl-arginine N-methylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0016277	P	Seeded From UniProt	complete
involved_in	GO:0035247	peptidyl-arginine omega-N-methylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0035241	P	Seeded From UniProt	complete
involved_in	GO:0035247	peptidyl-arginine omega-N-methylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0035241	P	Seeded From UniProt	complete
involved_in	GO:0035247	peptidyl-arginine omega-N-methylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0035241	P	Seeded From UniProt	complete
involved_in	GO:0035247	peptidyl-arginine omega-N-methylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0035241	P	Seeded From UniProt	complete
involved_in	GO:0043985	histone H4-R3 methylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0044020	P	Seeded From UniProt	complete
enables	GO:0043021	ribonucleoprotein complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	F	Seeded From UniProt	complete
enables	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	F	Seeded From UniProt	complete
enables	GO:0035241	protein-arginine omega-N monomethyltransferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	F	Seeded From UniProt	complete
involved_in	GO:0018216	peptidyl-arginine methylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	P	Seeded From UniProt	complete
involved_in	GO:0016571	histone methylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	P	Seeded From UniProt	complete
enables	GO:0016277	[myelin basic protein]-arginine N-methyltransferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	F	Seeded From UniProt	complete
enables	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	F	Seeded From UniProt	complete
enables	GO:0008469	histone-arginine N-methyltransferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	F	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	C	Seeded From UniProt	complete
part_of	GO:0001650	fibrillar center	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	C	Seeded From UniProt	complete
involved_in	GO:0000387	spliceosomal snRNP assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9NVM4 ensembl:ENSP00000343103	P	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A024R726 ensembl:ENSP00000343103	C	Seeded From UniProt	complete
part_of	GO:0001650	fibrillar center	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A024R726 ensembl:ENSP00000343103	C	Seeded From UniProt	complete
involved_in	GO:0006479	protein methylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014644 InterPro:IPR025799	P	Seeded From UniProt	complete
enables	GO:0008168	methyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014644 InterPro:IPR025799	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P	Seeded From UniProt	complete
enables	GO:0008168	methyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0489	F	Seeded From UniProt	complete
involved_in	GO:0006325	chromatin organization	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0156	P	Seeded From UniProt	complete
involved_in	GO:0032259	methylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0489	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0091	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Jelinic, P et al. (2006) The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation. PLoS Biol. 4 e355 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:17048991-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Jelinic, P et al. (2006) The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation. PLoS Biol. 4 e355 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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MOUSE:ANM7

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Annotations

Notes

References

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