Category:GO:0032933 ! SREBP signaling pathway

name: SREBP signaling pathway
namespace: biological_process
alt_id: GO:0006994
alt_id: GO:0030967
alt_id: GO:0035104
def: "The series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription." [GOC:bf, GOC:mah, GOC:signaling, GOC:vw, PMID:12923525, PMID:22017871]
synonym: "activation of sterol regulatory element binding protein target gene transcription" NARROW []
synonym: "endoplasmic reticulum to nucleus sterol response pathway" EXACT []
synonym: "endoplasmic reticulum-nuclear sterol response pathway" EXACT []
synonym: "ER to nucleus sterol response pathway" EXACT []
synonym: "ER-nuclear sterol response pathway" EXACT []
synonym: "positive regulation of sterol regulatory element binding protein target gene transcription" EXACT [GOC:dph, GOC:tb]
synonym: "positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response" EXACT [GOC:dph, GOC:tb]
synonym: "positive regulation of transcription via sterol regulatory element binding" NARROW [GOC:vw]
synonym: "positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway" NARROW [GOC:vw]
synonym: "SREBP signalling" EXACT [GOC:bf]
synonym: "SREBP target gene transcriptional activation" EXACT []
synonym: "SREBP-mediated signaling pathway" RELATED []
synonym: "SREBP-mediated signalling pathway" EXACT []
synonym: "sterol depletion response, SREBP target gene transcriptional activation" EXACT [GOC:dph, GOC:mtg_lung]
synonym: "sterol regulatory element binding protein target gene transcriptional activation" BROAD []
synonym: "sterol response element binding protein signaling pathway" EXACT [GOC:bf]
synonym: "stimulation of sterol regulatory element binding protein target gene transcription" NARROW []
synonym: "up regulation of sterol regulatory element binding protein target gene transcription" EXACT []
synonym: "up-regulation of sterol regulatory element binding protein target gene transcription" EXACT []
synonym: "upregulation of sterol regulatory element binding protein target gene transcription" EXACT []
is_a: GO:0006984 ! ER-nucleus signaling pathway
is_a: GO:0071501 ! cellular response to sterol depletion

AmiGO <GOterm>GO:0032933</GOterm>
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