Category:GO:0004467 ! long-chain fatty acid-CoA ligase activity

name: long-chain fatty acid-CoA ligase activity
namespace: molecular_function
alt_id: GO:0003996
def: "Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons." [RHEA:15421]
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283). Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
synonym: "acyl-activating enzyme activity" BROAD []
synonym: "acyl-CoA ligase activity" RELATED []
synonym: "acyl-CoA synthetase activity" RELATED [EC:6.2.1.3]
synonym: "fatty acid thiokinase (long-chain) activity" RELATED []
synonym: "LCFA synthetase activity" RELATED []
synonym: "lignoceroyl-CoA synthase activity" RELATED []
synonym: "long chain fatty acyl-CoA synthetase activity" RELATED []
synonym: "long-chain acyl CoA synthetase activity" RELATED []
synonym: "long-chain acyl-CoA synthetase activity" EXACT []
synonym: "long-chain acyl-coenzyme A synthetase activity" RELATED []
synonym: "long-chain fatty acid activation" RELATED []
synonym: "long-chain fatty acyl coenzyme A synthetase activity" RELATED []
synonym: "long-chain-fatty-acid-CoA ligase activity" EXACT []
synonym: "long-chain-fatty-acyl-CoA synthetase activity" EXACT []
synonym: "pristanoyl-CoA synthetase" NARROW []
synonym: "stearoyl-CoA synthetase" NARROW []
synonym: "thiokinase" RELATED []
xref: EC:6.2.1.3
xref: MetaCyc:RXN-7904
xref: RHEA:15421
is_a: GO:0120515 ! fatty acid-CoA ligase activity
relationship: part_of: GO:0001676 ! long-chain fatty acid metabolic process

AmiGO <GOterm>GO:0004467</GOterm>
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