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Category:GO:0003905 ! alkylbase DNA N-glycosylase activity
name: alkylbase DNA N-glycosylase activity
namespace: molecular_function
alt_id: GO:0004036
def: "Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site." [EC:3.2.2.21, GOC:elh, PMID:10872450, PMID:9224623]
synonym: "3-methyladenine DNA glycosylase II" RELATED [EC:3.2.2.21]
synonym: "AlkA" RELATED [EC:3.2.2.21]
synonym: "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)" BROAD [EC:3.2.2.21]
synonym: "alkylbase DNA glycosidase activity" EXACT []
synonym: "deoxyribonucleate 3-methyladenine glycosidase II" RELATED [EC:3.2.2.21]
synonym: "DNA glycosidase II activity" RELATED [EC:3.2.2.21]
synonym: "DNA-3-methyladenine glycosidase II activity" EXACT []
synonym: "DNA-3-methyladenine glycosylase II" RELATED [EC:3.2.2.21]
xref: EC:3.2.2.21
xref: MetaCyc:3.2.2.21-RXN
is_a: GO:0019104 ! DNA N-glycosylase activity
AmiGO
<GOterm>GO:0003905</GOterm>
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This category has the following 5 subcategories, out of 5 total.
