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Category:GO:0001913 ! T cell mediated cytotoxicity
name: T cell mediated cytotoxicity
namespace: biological_process
def: "The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, GOC:pr, ISBN:0781735149, PMID:11911826]
comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, independently of their definition as 'helper' T cells or not.
synonym: "T cell mediated apoptosis" EXACT []
synonym: "T cell mediated cell death" EXACT []
synonym: "T cell mediated cell killing" EXACT []
synonym: "T cell mediated cytolysis" RELATED []
synonym: "T lymphocyte mediated cytotoxicity" EXACT []
synonym: "T-cell mediated apoptosis" EXACT []
synonym: "T-cell mediated cell death" EXACT []
synonym: "T-cell mediated cell killing" EXACT []
synonym: "T-cell mediated cytotoxicity" EXACT []
synonym: "T-lymphocyte mediated cytotoxicity" EXACT []
is_a: GO:0001909 ! leukocyte mediated cytotoxicity
is_a: GO:0002456 ! T cell mediated immunity
AmiGO
<GOterm>GO:0001913</GOterm>
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This category has the following 4 subcategories, out of 4 total.
