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CHICK:RFA1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) RPA1
Protein Name(s) Replication protein A 70 kDa DNA-binding subunit

RP-A p70 Replication factor A protein 1 RF-A protein 1

External Links
UniProt Q5ZJJ2
EMBL AJ720442
RefSeq NP_001006221.1
UniGene Gga.4736
ProteinModelPortal Q5ZJJ2
SMR Q5ZJJ2
STRING 9031.ENSGALP00000004840
PaxDb Q5ZJJ2
PRIDE Q5ZJJ2
Ensembl ENSGALT00000004849
GeneID 417563
KEGG gga:417563
CTD 6117
eggNOG COG1599
GeneTree ENSGT00390000012403
HOGENOM HOG000162322
HOVERGEN HBG010502
InParanoid Q5ZJJ2
KO K07466
OMA GRRLIMN
OrthoDB EOG7GXPBM
PhylomeDB Q5ZJJ2
TreeFam TF105241
Reactome REACT_115585
REACT_115867
REACT_115931
REACT_197522
REACT_224142
REACT_227032
REACT_237891
REACT_241356
REACT_242347
REACT_247298
REACT_249594
REACT_251811
REACT_252323
REACT_254546
REACT_260639
REACT_261583
REACT_262071
NextBio 20820847
PRO PR:Q5ZJJ2
Proteomes UP000000539
GO GO:0015629
GO:0005737
GO:0005662
GO:0000800
GO:0001673
GO:0005654
GO:0005634
GO:0016605
GO:0003682
GO:0003684
GO:0046872
GO:0003697
GO:0006284
GO:0006281
GO:0006260
GO:0006302
GO:0000724
GO:0030097
GO:0048873
GO:0007126
GO:0006298
GO:0006289
GO:0008284
GO:0000723
Gene3D 2.40.50.140
InterPro IPR012340
IPR004365
IPR013955
IPR007199
IPR004591
Pfam PF04057
PF08646
PF01336
SUPFAM SSF50249
TIGRFAMs TIGR00617

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0003684

damaged DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P27694

F

Seeded From UniProt

complete

involved_in

GO:0034502

protein localization to chromosome

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P27694

P

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P27694

P

Seeded From UniProt

complete

part_of

GO:0005662

DNA replication factor A complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P27694

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P27694

C

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P27694

F

Seeded From UniProt

complete

involved_in

GO:0051321

meiotic cell cycle

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1915525
PANTHER:PTN000588618

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
SGD:S000000065

F

Seeded From UniProt

complete

enables

GO:0043047

single-stranded telomeric DNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
PomBase:SPBC660.13c

F

Seeded From UniProt

complete

involved_in

GO:0007004

telomere maintenance via telomerase

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
PomBase:SPBC660.13c
SGD:S000000065

P

Seeded From UniProt

complete

involved_in

GO:0006289

nucleotide-excision repair

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
SGD:S000000065
UniProtKB:P27694

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
PomBase:SPBC660.13c
SGD:S000000065
UniProtKB:P27694
UniProtKB:Q6YZ49

P

Seeded From UniProt

complete

involved_in

GO:0006268

DNA unwinding involved in DNA replication

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
PomBase:SPBC660.13c
SGD:S000000065

P

Seeded From UniProt

complete

involved_in

GO:0006261

DNA-dependent DNA replication

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010173
PANTHER:PTN000588618
UniProtKB:Q9U0J0

P

Seeded From UniProt

complete

part_of

GO:0005662

DNA replication factor A complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010173
PANTHER:PTN000588618
PomBase:SPBC660.13c
RGD:1307376
SGD:S000000065
UniProtKB:P27694
UniProtKB:Q10Q08

C

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010173
PANTHER:PTN000588618
PomBase:SPBC660.13c
RGD:1307376
SGD:S000000065
UniProtKB:P27694

F

Seeded From UniProt

complete

enables

GO:0003684

damaged DNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
UniProtKB:P27694

F

Seeded From UniProt

complete

part_of

GO:0000784

nuclear chromosome, telomeric region

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
PomBase:SPBC660.13c

C

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1915525
PANTHER:PTN000588618
SGD:S000000065
UniProtKB:P27694

P

Seeded From UniProt

complete

involved_in

GO:0000723

telomere maintenance

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588618
PomBase:SPBC660.13c
UniProtKB:P27694

P

Seeded From UniProt

complete

enables

GO:0098505

G-rich strand telomeric DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

F

Seeded From UniProt

complete

part_of

GO:0090734

site of DNA damage

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

C

Seeded From UniProt

complete

involved_in

GO:0034502

protein localization to chromosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

part_of

GO:0016605

PML body

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

C

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

involved_in

GO:0006298

mismatch repair

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

involved_in

GO:0006289

nucleotide-excision repair

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

involved_in

GO:0006284

base-excision repair

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

part_of

GO:0005662

DNA replication factor A complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

C

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

F

Seeded From UniProt

complete

enables

GO:0003684

damaged DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

F

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

involved_in

GO:0000723

telomere maintenance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27694
ensembl:ENSP00000254719

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004365

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004591
InterPro:IPR007199

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004591
InterPro:IPR007199

C

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004591
InterPro:IPR007199

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004591

P

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004591

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

Reactome:R-GGA-353377

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-GGA-353476
Reactome:R-GGA-265887
Reactome:R-GGA-265867

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

Reactome:R-GGA-351468
Reactome:R-GGA-351451

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

part_of

GO:0016605

PML body

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0465

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page