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CHICK:NKX25
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | NKX-2.5 (synonyms: NKX2E) | |
| Protein Name(s) | Homeobox protein Nkx-2.5
cNKx-2.5 Homeobox protein NK-2 homolog E | |
| External Links | ||
| UniProt | Q90788 | |
| EMBL | X91838 | |
| RefSeq | NP_990495.1 | |
| UniGene | Gga.638 | |
| ProteinModelPortal | Q90788 | |
| SMR | Q90788 | |
| STRING | 9031.ENSGALP00000004542 | |
| GeneID | 396073 | |
| KEGG | gga:396073 | |
| CTD | 1482 | |
| eggNOG | NOG310976 | |
| HOGENOM | HOG000231923 | |
| HOVERGEN | HBG006689 | |
| InParanoid | Q90788 | |
| KO | K09345 | |
| PhylomeDB | Q90788 | |
| NextBio | 20816132 | |
| Proteomes | UP000000539 | |
| GO | GO:0005634 GO:0043565 GO:0007275 GO:0006355 | |
| Gene3D | 1.10.10.60 | |
| InterPro | IPR017970 IPR001356 IPR020479 IPR009057 | |
| Pfam | PF00046 | |
| PRINTS | PR00024 | |
| SMART | SM00389 | |
| SUPFAM | SSF46689 | |
| PROSITE | PS00027 PS50071 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071772 |
response to BMP |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0004110 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000576 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000576 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000576 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261930 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108015 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006357 |
regulation of transcription by RNA polymerase II |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007507 |
heart development |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060048 |
cardiac muscle contraction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1903779 |
regulation of cardiac conduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lee, KH et al. (2004) SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer. Development 131 4709-23 PubMed GONUTS page
- ↑ Bai, C et al. (2013) Identification and biological characterization of chicken embryonic cardiac progenitor cells. Cell Prolif. 46 232-42 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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