GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

CHICK:HSF1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HSF1
Protein Name(s) Heat shock factor protein 1

HSF 1 HSF 3A HSTF 3A Heat shock transcription factor 1 HSTF 1

External Links
UniProt P38529
EMBL L06098
RefSeq NP_001292185.1
UniGene Gga.51526
ProteinModelPortal P38529
SMR P38529
PRIDE P38529
GeneID 420362
eggNOG COG5169
HOVERGEN HBG005999
InParanoid P38529
PhylomeDB P38529
Proteomes UP000000539
GO GO:0005737
GO:0005634
GO:0043565
GO:0003700
GO:0009408
GO:0006351
Gene3D 1.10.10.10
InterPro IPR027072
IPR000232
IPR027725
IPR010542
IPR011991
PANTHER PTHR10015
PTHR10015:SF142
Pfam PF00447
PF06546
PRINTS PR00056
SMART SM00415
PROSITE PS00434

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0000165

MAPK cascade

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0061408

positive regulation of transcription from RNA polymerase II promoter in response to heat stress

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

part_of

GO:0097165

nuclear stress granule

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

part_of

GO:0016605

PML body

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

involved_in

GO:0071276

cellular response to cadmium ion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

F

Seeded From UniProt

complete

involved_in

GO:0070207

protein homotrimerization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0051260

protein homooligomerization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

enables

GO:0043621

protein self-association

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

F

Seeded From UniProt

complete

part_of

GO:0097431

mitotic spindle pole

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

part_of

GO:0005813

centrosome

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

part_of

GO:0000776

kinetochore

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

involved_in

GO:0045931

positive regulation of mitotic cell cycle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

enables

GO:0031490

chromatin DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

F

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

C

Seeded From UniProt

complete

involved_in

GO:1900365

positive regulation of mRNA polyadenylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

enables

GO:0031072

heat shock protein binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

F

Seeded From UniProt

complete

enables

GO:1990841

promoter-specific chromatin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

F

Seeded From UniProt

complete

involved_in

GO:0034605

cellular response to heat

PMID:11387221[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:11387221[1]

ECO:0000314

direct assay evidence used in manual assertion

F

part_of:(GO:0034605)

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:11387221[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

part_of:(GO:0034605)|part_of:(GO:1903936)|part_of:(GO:0071417)|has_regulation_target(UniProtKB:P11501)

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:11387221[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

part_of:(GO:0034605)|part_of:(GO:0071478)|part_of:(GO:1903936)

Seeded From UniProt

complete

involved_in

GO:1902808

positive regulation of cell cycle G1/S phase transition

PMID:11387221[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

part_of:(GO:0034605)

Seeded From UniProt

complete

involved_in

GO:1902751

positive regulation of cell cycle G2/M phase transition

PMID:11387221[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

part_of:(GO:0034605)

Seeded From UniProt

complete

involved_in

GO:0070207

protein homotrimerization

PMID:9716376[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:9716376[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009408

response to heat

PMID:9716376[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0001046

core promoter sequence-specific DNA binding

PMID:9716376[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009416

response to light stimulus

PMID:21383147[3]

ECO:0000314

direct assay evidence used in manual assertion

P

part_of:(UBERON:0001905)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21383147[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0001905)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:10504401[4]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0000970)|part_of:(UBERON:0000955)|part_of:(CL:0000232)|part_of:(UBERON:0002048)|part_of:(UBERON:0000948)|part_of:(UBERON:0002107)|part_of:(UBERON:0002113)|part_of:(UBERON:0005052)|part_of:(UBERON:0000160)|part_of:(UBERON:0003903)|part_of:(UBERON:0002342)|part_of:(UBERON:0002329)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:10504401[4]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0000970)|part_of:(UBERON:0000955)|part_of:(CL:0000232)|part_of:(UBERON:0002048)|part_of:(UBERON:0000948)|part_of:(UBERON:0002107)|part_of:(UBERON:0002113)|part_of:(UBERON:0005052)|part_of:(UBERON:0000160)|part_of:(UBERON:0003903)|part_of:(UBERON:0002342)|part_of:(UBERON:0002329)

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:10504401[4]

ECO:0000314

direct assay evidence used in manual assertion

F

part_of:(GO:0009408)

Seeded From UniProt

complete

involved_in

GO:2001033

negative regulation of double-strand break repair via nonhomologous end joining

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0071480

cellular response to gamma radiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0043497

regulation of protein heterodimerization activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q00613

P

Seeded From UniProt

complete

involved_in

GO:0061408

positive regulation of transcription from RNA polymerase II promoter in response to heat stress

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000001154
UniProtKB:Q00613

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001222
MGI:MGI:1347058
MGI:MGI:3045337
MGI:MGI:96238
MGI:MGI:96239
PANTHER:PTN000001154
RGD:1310808
SGD:S000005666
UniProtKB:P38529
UniProtKB:P38531
UniProtKB:Q00613
ZFIN:ZDB-GENE-000616-16
ZFIN:ZDB-GENE-011128-1
ZFIN:ZDB-GENE-050306-18

F

Seeded From UniProt

complete

involved_in

GO:0034605

cellular response to heat

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:3045337
PANTHER:PTN000001154
RGD:620913
UniProtKB:O80982
UniProtKB:P38529
UniProtKB:P38531
UniProtKB:Q00613

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000195882
FB:FBgn0001222
MGI:MGI:3045337
MGI:MGI:96238
MGI:MGI:96239
PANTHER:PTN000001154
PomBase:SPAC2E12.02
PomBase:SPAC8C9.14
RGD:1310808
RGD:620913
SGD:S000001249
SGD:S000003041
SGD:S000005666
TAIR:locus:2005495
TAIR:locus:2075447
TAIR:locus:2117139
TAIR:locus:2144603
TAIR:locus:2149050
UniProtKB:I1LGH5
UniProtKB:I1MPZ9
UniProtKB:K7LH36
UniProtKB:O80982
UniProtKB:P38529
UniProtKB:P38530
UniProtKB:P38531
UniProtKB:Q00613
UniProtKB:Q43457
UniProtKB:Q5A287
UniProtKB:Q942D6
UniProtKB:Q9UBD0
WB:WBGene00002004

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000195882
FB:FBgn0001222
PANTHER:PTN000001154
SGD:S000001249
SGD:S000003041
TAIR:locus:2149050

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96238
MGI:MGI:96239
PANTHER:PTN000001154
PomBase:SPAC2E12.02
PomBase:SPAC8C9.14
SGD:S000005666
UniProtKB:Q00613

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010542

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000232
InterPro:IPR010542

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000232

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000232
InterPro:IPR010542

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000232

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0000775

chromosome, centromeric region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0137

C

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

part_of

GO:0000776

kinetochore

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0995

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158

C

Seeded From UniProt

complete

involved_in

GO:0051028

mRNA transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0509

P

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

part_of

GO:0000777

condensed chromosome kinetochore

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0149

C

Seeded From UniProt

complete

part_of

GO:0000922

spindle pole

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0448

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0190

C

Seeded From UniProt

complete

part_of

GO:0005815

microtubule organizing center

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0048

C

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0198

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Nakai, A & Ishikawa, T (2001) Cell cycle transition under stress conditions controlled by vertebrate heat shock factors. EMBO J. 20 2885-95 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Kawazoe, Y et al. (1998) Proteasome inhibition leads to the activation of all members of the heat-shock-factor family. Eur. J. Biochem. 255 356-62 PubMed GONUTS page
  3. 3.0 3.1 Hatori, M et al. (2011) Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1, and heat shock factor pathways. Proc. Natl. Acad. Sci. U.S.A. 108 4864-9 PubMed GONUTS page
  4. 4.0 4.1 4.2 Kawazoe, Y et al. (1999) HSF3 is a major heat shock responsive factor duringchicken embryonic development. Eur. J. Biochem. 265 688-97 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page