CHICK:DICER

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	DICER1 (synonyms: DICER)
Protein Name(s)	Endoribonuclease Dicer
External Links
UniProt	Q25BN1
EMBL	AB253768
RefSeq	NP_001035555.1
UniGene	Gga.33735
ProteinModelPortal	Q25BN1
SMR	Q25BN1
PaxDb	Q25BN1
GeneID	423437
KEGG	gga:423437
CTD	23405
eggNOG	COG1111
HOGENOM	HOG000001567
InParanoid	Q25BN1
KO	K11592
PhylomeDB	Q25BN1
NextBio	20825910
PRO	PR:Q25BN1
Proteomes	UP000000539
GO	GO:0005737 GO:0016442 GO:0005524 GO:0004386 GO:0046872 GO:0004525 GO:0003723 GO:0031054 GO:0030422 GO:0030423
Gene3D	1.10.1520.10 3.30.160.20 3.40.50.300
InterPro	IPR011545 IPR005034 IPR014720 IPR014001 IPR001650 IPR027417 IPR003100 IPR000999
Pfam	PF00270 PF03368 PF00271 PF02170 PF00636
SMART	SM00487 SM00358 SM00490 SM00949 SM00535
SUPFAM	SSF101690 SSF52540 SSF69065
PROSITE	PS51327 PS50137 PS51192 PS51194 PS50821 PS00517 PS50142

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0035068	micro-ribonucleoprotein complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UPY3	C	Seeded From UniProt	complete
involved_in	GO:0031054	pre-miRNA processing	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UPY3	P	Seeded From UniProt	complete
involved_in	GO:0030423	targeting of mRNA for destruction involved in RNA interference	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UPY3	P	Seeded From UniProt	complete
involved_in	GO:0030422	production of siRNA involved in RNA interference	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UPY3	P	Seeded From UniProt	complete
part_of	GO:0070578	RISC-loading complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UPY3	C	Seeded From UniProt	complete
involved_in	GO:0030422	production of siRNA involved in RNA interference	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034246 FB:FBgn0039016 MGI:MGI:2177178 PANTHER:PTN000383724 PomBase:SPCC188.13c UniProtKB:Q9LXW7 UniProtKB:Q9UPY3 WB:WBGene00000939	P	Seeded From UniProt	complete
part_of	GO:0016442	RISC complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034246 FB:FBgn0039016 PANTHER:PTN000383724 UniProtKB:Q9UPY3	C	Seeded From UniProt	complete
involved_in	GO:0006309	apoptotic DNA fragmentation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001029377 WB:WBGene00000939	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034246 FB:FBgn0039016 MGI:MGI:2177178 PANTHER:PTN000383724 PomBase:SPCC188.13c TAIR:locus:2092409 WB:WBGene00000939	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034246 FB:FBgn0039016 PANTHER:PTN000383724 PomBase:SPCC188.13c TAIR:locus:2092409 UniProtKB:P84634 UniProtKB:Q9LXW7 UniProtKB:Q9SP32 WB:WBGene00000939	C	Seeded From UniProt	complete
enables	GO:0004530	deoxyribonuclease I activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001029377 WB:WBGene00000939	F	Seeded From UniProt	complete
enables	GO:0004525	ribonuclease III activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034246 MGI:MGI:2177178 PANTHER:PTN000383724 TAIR:locus:2092409 UniProtKB:Q9UPY3 WB:WBGene00000939	F	Seeded From UniProt	complete
involved_in	GO:0031054	pre-miRNA processing	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034246 FB:FBgn0039016 MGI:MGI:2177178 PANTHER:PTN001029377 UniProtKB:Q9UPY3 WB:WBGene00000939	P	Seeded From UniProt	complete
involved_in	GO:0090501	RNA phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004525	P	Seeded From UniProt	complete
involved_in	GO:0090501	RNA phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004525	P	Seeded From UniProt	complete
involved_in	GO:0090501	RNA phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004525	P	Seeded From UniProt	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004525	P	Seeded From UniProt	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0016891	P	Seeded From UniProt	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004525	P	Seeded From UniProt	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004525	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006935	F	Seeded From UniProt	complete
enables	GO:0004525	ribonuclease III activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000999 InterPro:IPR036389	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006935	F	Seeded From UniProt	complete
involved_in	GO:0006396	RNA processing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000999 InterPro:IPR036389	P	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006935	F	Seeded From UniProt	complete
enables	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005034	F	Seeded From UniProt	complete
enables	GO:0004525	ribonuclease III activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.26.3	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F	Seeded From UniProt	complete
involved_in	GO:0031047	gene silencing by RNA	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0943	P	Seeded From UniProt	complete
enables	GO:0004386	helicase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0347	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F	Seeded From UniProt	complete
enables	GO:0004519	endonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0255	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:DICER

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Notes

References

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