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CAEEL:G5EES3

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) No Information Provided.
Protein Name(s) Protein argonaute (ECO:0000256 with RuleBase:RU361178)
External Links
UniProt G5EES3
EMBL Z69661
Z69663
RefSeq NP_001257239.1
UniGene Cel.5579
ProteinModelPortal G5EES3
SMR G5EES3
EnsemblMetazoa F48F7.1b
GeneID 181504
KEGG cel:CELE_F48F7.1
CTD 181504
WormBase F48F7.1b
GeneTree ENSGT00760000119148
InParanoid G5EES3
KO K11593
OMA FKHLKYT
Reactome REACT_182979
REACT_183789
REACT_258001
Proteomes UP000001940
ExpressionAtlas G5EES3
GO GO:0005737
GO:0000932
GO:0035068
GO:0035198
GO:0009792
GO:0031047
GO:0040035
GO:0002119
GO:0040025
Gene3D 3.30.420.10
InterPro IPR014811
IPR003100
IPR003165
IPR012337
Pfam PF08699
PF02170
PF02171
SMART SM00949
SM00950
SUPFAM SSF101690
SSF53098
PROSITE PS50821
PS50822

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0040034

regulation of development, heterochronic

PMID:25432023[1]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P42573

P

Seeded From UniProt

complete

involved_in

GO:0042659

regulation of cell fate specification

PMID:25432023[1]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P42573

P

Seeded From UniProt

complete

involved_in

GO:0070922

small RNA loading onto RISC

PMID:22904066[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035196

production of miRNAs involved in gene silencing by miRNA

PMID:22904066[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003727

single-stranded RNA binding

PMID:22904066[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003725

double-stranded RNA binding

PMID:22904066[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016892

endoribonuclease activity, producing 3'-phosphomonoesters

PMID:22904066[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0035279

mRNA cleavage involved in gene silencing by miRNA

PMID:22904066[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0040035

hermaphrodite genitalia development

PMID:11461699[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0040025

vulval development

PMID:11461699[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0035198

miRNA binding

PMID:19734881[4]

ECO:0000353

physical interaction evidence used in manual assertion

WB:WBGene00002285

F

Seeded From UniProt

complete

part_of

GO:0035068

micro-ribonucleoprotein complex

PMID:15024405[5]

ECO:0000353

physical interaction evidence used in manual assertion

WB:WBGene00000106
WB:WBGene00002285

C

Seeded From UniProt

complete

involved_in

GO:0009792

embryo development ending in birth or egg hatching

PMID:11461699[3]

ECO:0000316

genetic interaction evidence used in manual assertion

WB:WBGene00000106

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:16109369[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0002119

nematode larval development

PMID:11461699[3]

ECO:0000316

genetic interaction evidence used in manual assertion

WB:WBGene00000106

P

Seeded From UniProt

complete

part_of

GO:0000932

P-body

PMID:16109369[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016892

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003165
InterPro:IPR036397

F

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Weaver, BP et al. (2014) CED-3 caspase acts with miRNAs to regulate non-apoptotic gene expression dynamics for robust development in C. elegans. Elife 3 e04265 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Bouasker, S & Simard, MJ (2012) The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans. Nucleic Acids Res. 40 10452-62 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 Grishok, A et al. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106 23-34 PubMed GONUTS page
  4. ↑ Chatterjee, S & Grosshans, H (2009) Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461 546-9 PubMed GONUTS page
  5. ↑ Hutvágner, G et al. (2004) Sequence-specific inhibition of small RNA function. PLoS Biol. 2 E98 PubMed GONUTS page
  6. ↑ 6.0 6.1 Ding, L et al. (2005) The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Mol. Cell 19 437-47 PubMed GONUTS page
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