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CAEEL:G5EES3

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) No Information Provided.
Protein Name(s) Protein argonaute (ECO:0000256 with RuleBase:RU361178)
External Links
UniProt G5EES3
EMBL Z69661
Z69663
RefSeq NP_001257239.1
UniGene Cel.5579
ProteinModelPortal G5EES3
SMR G5EES3
EnsemblMetazoa F48F7.1b
GeneID 181504
KEGG cel:CELE_F48F7.1
CTD 181504
WormBase F48F7.1b
GeneTree ENSGT00760000119148
InParanoid G5EES3
KO K11593
OMA FKHLKYT
Reactome REACT_182979
REACT_183789
REACT_258001
Proteomes UP000001940
ExpressionAtlas G5EES3
GO GO:0005737
GO:0000932
GO:0035068
GO:0035198
GO:0009792
GO:0031047
GO:0040035
GO:0002119
GO:0040025
Gene3D 3.30.420.10
InterPro IPR014811
IPR003100
IPR003165
IPR012337
Pfam PF08699
PF02170
PF02171
SMART SM00949
SM00950
SUPFAM SSF101690
SSF53098
PROSITE PS50821
PS50822

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000932

cytoplasmic mRNA processing body

PMID:16109369[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0002119

nematode larval development

PMID:11461699[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000106

P

Seeded From UniProt

complete

GO:0003676

nucleic acid binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003165
InterPro:IPR012337

F

Seeded From UniProt

complete

GO:0003725

double-stranded RNA binding

PMID:22904066[3]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0003727

single-stranded RNA binding

PMID:22904066[3]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:16109369[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0009792

embryo development ending in birth or egg hatching

PMID:11461699[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000106

P

Seeded From UniProt

complete

GO:0016892

endoribonuclease activity, producing 3'-phosphomonoesters

PMID:22904066[3]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0031047

gene silencing by RNA

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

GO:0035068

micro-ribonucleoprotein complex

PMID:15024405[4]

IPI: Inferred from Physical Interaction

WB:WBGene00000106
WB:WBGene00002285

C

Seeded From UniProt

complete

GO:0035196

production of miRNAs involved in gene silencing by miRNA

PMID:22904066[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0035198

miRNA binding

PMID:19734881[5]

IPI: Inferred from Physical Interaction

WB:WBGene00002285

F

Seeded From UniProt

complete

GO:0035279

mRNA cleavage involved in gene silencing by miRNA

PMID:22904066[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0040025

vulval development

PMID:11461699[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0040035

hermaphrodite genitalia development

PMID:11461699[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0070922

small RNA loading onto RISC

PMID:22904066[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

PMID:22904066[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ding, L et al. (2005) The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Mol. Cell 19 437-47 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Grishok, A et al. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106 23-34 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Bouasker, S & Simard, MJ (2012) The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans. Nucleic Acids Res. 40 10452-62 PubMed GONUTS page
  4. Hutvágner, G et al. (2004) Sequence-specific inhibition of small RNA function. PLoS Biol. 2 E98 PubMed GONUTS page
  5. Chatterjee, S & Grosshans, H (2009) Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461 546-9 PubMed GONUTS page