GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ARATH:AGO1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) AGO1
Protein Name(s) Protein argonaute 1
External Links
UniProt O04379
EMBL U91995
AC007932
AC020889
CP002684
CP002684
CP002684
BT000941
AK227868
RefSeq NP_001185169.1
NP_175274.1
NP_849784.1
UniGene At.21124
PDB 3VNA
3VNB
4G0P
4G0Q
4G0X
4G0Y
4G0Z
PDBsum 3VNA
3VNB
4G0P
4G0Q
4G0X
4G0Y
4G0Z
ProteinModelPortal O04379
SMR O04379
BioGrid 26487
IntAct O04379
PaxDb O04379
PRIDE O04379
EnsemblPlants AT1G48410.1
GeneID 841262
KEGG ath:AT1G48410
TAIR AT1G48410
eggNOG NOG279895
HOGENOM HOG000116043
InParanoid O04379
KO K11593
OMA KSLYTAN
PhylomeDB O04379
Reactome REACT_184981
REACT_190885
REACT_255398
REACT_269630
Proteomes UP000006548
ExpressionAtlas O04379
Genevestigator O04379
GO GO:0005737
GO:0005829
GO:0019898
GO:0005634
GO:0030529
GO:0004521
GO:0046872
GO:0035198
GO:0003723
GO:0035197
GO:0009955
GO:0048830
GO:0009850
GO:0006952
GO:0009793
GO:0035195
GO:0031047
GO:0045087
GO:0009965
GO:0010589
GO:0010305
GO:0007275
GO:0016441
GO:0006355
GO:0006417
GO:0009733
GO:0010218
GO:0016246
GO:0090502
GO:0048864
GO:0006351
GO:0016032
GO:0009616
Gene3D 3.30.420.10
InterPro IPR024357
IPR014811
IPR003100
IPR003165
IPR012337
Pfam PF08699
PF12764
PF02170
PF02171
SMART SM00949
SM00950
SUPFAM SSF101690
SSF53098
PROSITE PS50821
PS50822

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005737

cytoplasm

PMID:28463111[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:18653559[2]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:Q9XGW1

P

Seeded From UniProt

complete

enables

GO:0035198

miRNA binding

PMID:16998468[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0060145

viral gene silencing in virus induced gene silencing

PMID:18799732[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051607

defense response to virus

PMID:26023161[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048830

adventitious root development

PMID:15829601[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

PMID:20164210[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0035198

miRNA binding

PMID:30181559[8]

ECO:0000353

physical interaction evidence used in manual assertion

AGI_LocusCode:AT3G50100

F

Seeded From UniProt

complete

involved_in

GO:0035195

gene silencing by miRNA

PMID:15131082[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035195

gene silencing by miRNA

PMID:15131082[9]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016441

posttranscriptional gene silencing

PMID:11910010[10]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010589

leaf proximal/distal pattern formation

PMID:22623415[11]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010305

leaf vascular tissue pattern formation

PMID:22623415[11]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010218

response to far red light

PMID:15829601[6]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT1G09570

P

Seeded From UniProt

complete

involved_in

GO:0009965

leaf morphogenesis

PMID:9427751[12]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009955

adaxial/abaxial pattern specification

PMID:22623415[11]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009850

auxin metabolic process

PMID:15829601[6]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT4G31500

P

Seeded From UniProt

complete

involved_in

GO:0009733

response to auxin

PMID:15829601[6]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT4G31500

P

Seeded From UniProt

complete

involved_in

GO:0009616

virus induced gene silencing

PMID:17158744[13]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18433157[14]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:22247253[15]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:17442570[16]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:22247253[15]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:17442570[16]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004521

endoribonuclease activity

PMID:16081530[17]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003729

mRNA binding

PMID:27729395[18]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004521

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003165
InterPro:IPR036397

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:9427751[12]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

GO:0060145

viral gene silencing in virus induced gene silencing

PMID:18799732[4]

ECO:0000315

P

Supplemental Figure S5. shows that ago1-11 mutants (which have partial loss of AGO1 function) have higher levels of ΔCP RNA accumulation than wild-type when infected with a turnip crinkle virus (TCV) mutant without a silencing suppressor.

complete
CACAO 8228

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0611

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

involved_in

GO:0006417

regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0810

P

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Zhang, Z et al. (2017) RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in . Elife 6 PubMed GONUTS page
  2. ↑ Tucker, MR et al. (2008) Vascular signalling mediated by ZWILLE potentiates WUSCHEL function during shoot meristem stem cell development in the Arabidopsis embryo. Development 135 2839-43 PubMed GONUTS page
  3. ↑ Qi, Y et al. (2006) Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation. Nature 443 1008-12 PubMed GONUTS page
  4. ↑ 4.0 4.1 Qu, F et al. (2008) Arabidopsis DRB4, AGO1, AGO7, and RDR6 participate in a DCL4-initiated antiviral RNA silencing pathway negatively regulated by DCL1. Proc. Natl. Acad. Sci. U.S.A. 105 14732-7 PubMed GONUTS page
  5. ↑ Brosseau, C & Moffett, P (2015) Functional and Genetic Analysis Identify a Role for Arabidopsis ARGONAUTE5 in Antiviral RNA Silencing. Plant Cell 27 1742-54 PubMed GONUTS page
  6. ↑ 6.0 6.1 6.2 6.3 Sorin, C et al. (2005) Auxin and light control of adventitious rooting in Arabidopsis require ARGONAUTE1. Plant Cell 17 1343-59 PubMed GONUTS page
  7. ↑ Li, Y et al. (2010) Identification of microRNAs involved in pathogen-associated molecular pattern-triggered plant innate immunity. Plant Physiol. 152 2222-31 PubMed GONUTS page
  8. ↑ Chen, J et al. (2018) Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. Nat Commun 9 3585 PubMed GONUTS page
  9. ↑ 9.0 9.1 Vaucheret, H et al. (2004) The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development. Genes Dev. 18 1187-97 PubMed GONUTS page
  10. ↑ Morel, JB et al. (2002) Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance. Plant Cell 14 629-39 PubMed GONUTS page
  11. ↑ 11.0 11.1 11.2 Jover-Gil, S et al. (2012) The microRNA pathway genes AGO1, HEN1 and HYL1 participate in leaf proximal-distal, venation and stomatal patterning in Arabidopsis. Plant Cell Physiol. 53 1322-33 PubMed GONUTS page
  12. ↑ 12.0 12.1 Bohmert, K et al. (1998) AGO1 defines a novel locus of Arabidopsis controlling leaf development. EMBO J. 17 170-80 PubMed GONUTS page
  13. ↑ Zhang, X et al. (2006) Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. Genes Dev. 20 3255-68 PubMed GONUTS page
  14. ↑ de la Fuente van Bentem, S et al. (2008) Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis. J. Proteome Res. 7 2458-70 PubMed GONUTS page
  15. ↑ 15.0 15.1 Duan, CG et al. (2012) Suppression of Arabidopsis ARGONAUTE1-mediated slicing, transgene-induced RNA silencing, and DNA methylation by distinct domains of the Cucumber mosaic virus 2b protein. Plant Cell 24 259-74 PubMed GONUTS page
  16. ↑ 16.0 16.1 Fang, Y & Spector, DL (2007) Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants. Curr. Biol. 17 818-23 PubMed GONUTS page
  17. ↑ Baumberger, N & Baulcombe, DC (2005) Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits microRNAs and short interfering RNAs. Proc. Natl. Acad. Sci. U.S.A. 102 11928-33 PubMed GONUTS page
  18. ↑ Reichel, M et al. (2016) In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Plant Cell 28 2435-2452 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=ARATH:AGO1&oldid=5952722"