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YEAST:UMP1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | UMP1 | |
| Protein Name(s) | Proteasome maturation factor UMP1 | |
| External Links | ||
| UniProt | P38293 | |
| EMBL | AJ002557 Z36042 AY558126 BK006936 | |
| PIR | S46044 | |
| RefSeq | NP_009732.1 | |
| ProteinModelPortal | P38293 | |
| BioGrid | 32873 | |
| DIP | DIP-2815N | |
| IntAct | P38293 | |
| MINT | MINT-483112 | |
| STRING | 4932.YBR173C | |
| PaxDb | P38293 | |
| EnsemblFungi | [example_ID YBR173C] | |
| GeneID | 852471 | |
| KEGG | sce:YBR173C | |
| CYGD | YBR173c | |
| SGD | S000000377 | |
| eggNOG | NOG305309 | |
| HOGENOM | HOG000175329 | |
| InParanoid | P38293 | |
| KO | K11599 | |
| OMA | MVGDDVH | |
| OrthoDB | EOG7QG4GR | |
| BioCyc | YEAST:G3O-29121-MONOMER | |
| NextBio | 971429 | |
| PRO | PR:P38293 | |
| Proteomes | UP000002311 | |
| Genevestigator | P38293 | |
| GO | GO:0005737 GO:0005634 GO:0006974 GO:0043248 GO:0006511 | |
| InterPro | IPR008012 | |
| PANTHER | PTHR12828 | |
| Pfam | PF05348 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0090363 |
regulation of proteasome core complex assembly |
ECO:0000315 |
P |
Figure 4 (C). The blot of the gene ump1 mutant compared to the wild type blot, as long as the rest of the blots, indicate that the presence of ump1 is needed for regulation of core complex assembly due to the lack of regulatory particle and core particle bands. |
complete | |||||
|
involved_in |
GO:0090363 |
regulation of proteasome core complex assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043248 |
proteasome assembly |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000000137 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043248 |
proteasome assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043248 |
proteasome assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000302763 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1913787 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1913787 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043248 |
proteasome assembly |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Park, S et al. (2011) Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress response. J. Biol. Chem. 286 36652-66 PubMed GONUTS page
- ↑ Li, X et al. (2007) beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J. 26 2339-49 PubMed GONUTS page
- ↑ 3.0 3.1 Ramos, PC et al. (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92 489-99 PubMed GONUTS page
- ↑ Mieczkowski, P et al. (2000) Expression of UMP1 is inducible by DNA damage and required for resistance of S. cerevisiae cells to UV light. Curr. Genet. 38 53-9 PubMed GONUTS page
- ↑ 5.0 5.1 Lehmann, A et al. (2002) 20 S proteasomes are imported as precursor complexes into the nucleus of yeast. J. Mol. Biol. 317 401-13 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
