GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
YEAST:NCB5R
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | CBR1 (synonyms: CBR, CBR5) | |
| Protein Name(s) | NADH-cytochrome b5 reductase 1
Microsomal cytochrome b reductase P35 | |
| External Links | ||
| UniProt | P38626 | |
| EMBL | Z28365 Z46861 BK006942 | |
| PIR | S49935 | |
| RefSeq | NP_012221.2 | |
| ProteinModelPortal | P38626 | |
| SMR | P38626 | |
| BioGrid | 34947 | |
| IntAct | P38626 | |
| MINT | MINT-1324688 | |
| MaxQB | P38626 | |
| PeptideAtlas | P38626 | |
| EnsemblFungi | YIL043C | |
| GeneID | 854768 | |
| KEGG | sce:YIL043C | |
| EuPathDB | FungiDB:YIL043C | |
| SGD | S000001305 | |
| GeneTree | ENSGT00390000008881 | |
| HOGENOM | HOG000175005 | |
| InParanoid | P38626 | |
| KO | K00326 | |
| OMA | CSAVQDA | |
| OrthoDB | EOG7N63XM | |
| BioCyc | YEAST:YIL043C-MONOMER | |
| Reactome | [www.reactome.org/content/detail/R-SCE-114608 R-SCE-114608] [www.reactome.org/content/detail/R-SCE-1237044 R-SCE-1237044] [www.reactome.org/content/detail/R-SCE-196836 R-SCE-196836] | |
| PRO | PR:P38626 | |
| Proteomes | UP000002311 | |
| GO | GO:0005789 GO:0016021 GO:0005741 GO:0004128 | |
| InterPro | IPR017927 IPR001709 IPR001834 IPR008333 IPR001433 IPR017938 | |
| Pfam | PF00970 PF00175 | |
| PRINTS | PR00406 PR00371 | |
| SUPFAM | SSF63380 | |
| PROSITE | PS51384 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003954 |
NADH dehydrogenase activity |
ECO:0000314 |
F |
The author expressed Cbr1 and monitored the reduction of Dph3 through Dph3's absorption at 488nm. The author then added NADH to the reaction tube and noticed that Cbr1 rapidly reduced Dph3 (this is shown is figure 1b). However, the author also found that Cbr1 did not reduce Dph3 upon addition of NADPH (supplemental figure 3). |
complete | |||||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008150 |
biological_process |
ECO:0000307 |
no biological data found used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004128 |
cytochrome-b5 reductase activity, acting on NAD(P)H |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000182794 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001433 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001433 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004128 |
cytochrome-b5 reductase activity, acting on NAD(P)H |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lin, Z et al. (2016) Cbr1 is a Dph3 reductase required for the tRNA wobble uridine modification. Nat. Chem. Biol. PubMed GONUTS page
- ↑ Reinders, J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J. Proteome Res. 5 1543-54 PubMed GONUTS page
- ↑ Zahedi, RP et al. (2006) Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol. Biol. Cell 17 1436-50 PubMed GONUTS page
- ↑ Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
- ↑ Renvoisé, M et al. (2014) Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. J Proteomics 106 140-50 PubMed GONUTS page
- ↑ Sickmann, A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc. Natl. Acad. Sci. U.S.A. 100 13207-12 PubMed GONUTS page
- ↑ Kubota, S et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J. Biochem. 81 187-95 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
