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YEAST:MET4
Contents
Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
Gene Name(s) | MET4 | |
Protein Name(s) | Transcriptional activator of sulfur metabolism MET4
Methionine-requiring protein 4 | |
External Links | ||
UniProt | P32389 | |
EMBL | M84455 Z12126 Z50161 Z71379 BK006947 | |
PIR | S63043 | |
RefSeq | NP_014296.4 | |
ProteinModelPortal | P32389 | |
SMR | P32389 | |
BioGrid | 35720 | |
DIP | DIP-2241N | |
IntAct | P32389 | |
MINT | MINT-438010 | |
STRING | 4932.YNL103W | |
MaxQB | P32389 | |
PaxDb | P32389 | |
PeptideAtlas | P32389 | |
GeneID | 855620 | |
KEGG | sce:YNL103W | |
SGD | S000005047 | |
eggNOG | NOG41133 | |
InParanoid | P32389 | |
OrthoDB | EOG7M98V6 | |
BioCyc | YEAST:G3O-33131-MONOMER | |
NextBio | 979810 | |
Proteomes | UP000002311 | |
Genevestigator | P32389 | |
GO | GO:0005634 GO:0043565 GO:0003700 GO:0003713 GO:0019344 GO:0009086 GO:0045944 GO:0046685 GO:0046686 GO:0000096 GO:0006351 | |
InterPro | IPR004827 | |
SMART | SM00338 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0089713 |
Cbf1-Met4-Met28 complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0089713 |
Cbf1-Met4-Met28 complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046686 |
response to cadmium ion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046685 |
response to arsenic-containing substance |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003713 |
transcription coactivator activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000096 |
sulfur amino acid metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009086 |
methionine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019344 |
cysteine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kuras, L et al. (1997) Assembly of a bZIP-bHLH transcription activation complex: formation of the yeast Cbf1-Met4-Met28 complex is regulated through Met28 stimulation of Cbf1 DNA binding. EMBO J. 16 2441-51 PubMed GONUTS page
- ↑ Kuras, L et al. (1996) A heteromeric complex containing the centromere binding factor 1 and two basic leucine zipper factors, Met4 and Met28, mediates the transcription activation of yeast sulfur metabolism. EMBO J. 15 2519-29 PubMed GONUTS page
- ↑ 3.0 3.1 Yen, JL et al. (2005) The yeast ubiquitin ligase SCFMet30 regulates heavy metal response. Mol. Biol. Cell 16 1872-82 PubMed GONUTS page
- ↑ McIsaac, RS et al. (2012) Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway. Mol. Biol. Cell 23 2993-3007 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Blaiseau, PL & Thomas, D (1998) Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA. EMBO J. 17 6327-36 PubMed GONUTS page
- ↑ Thomas, D et al. (1992) MET4, a leucine zipper protein, and centromere-binding factor 1 are both required for transcriptional activation of sulfur metabolism in Saccharomyces cerevisiae. Mol. Cell. Biol. 12 1719-27 PubMed GONUTS page