YEAST:LSB1

Species (Taxon ID)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s)	LSB1
Protein Name(s)	LAS seventeen-binding protein 1 LAS17-binding protein 1
External Links
UniProt	P53281
EMBL	Z72921 BK006941
PIR	S64445
RefSeq	NP_011652.1
ProteinModelPortal	P53281
SMR	P53281
BioGrid	33384
DIP	DIP-1863N
IntAct	P53281
MINT	MINT-375073
STRING	4932.YGR136W
MaxQB	P53281
PaxDb	P53281
PeptideAtlas	P53281
EnsemblFungi	[example_ID YGR136W]
GeneID	853037
KEGG	sce:YGR136W
CYGD	YGR136w
SGD	S000003368
eggNOG	NOG136033
GeneTree	ENSGT00510000054224
HOGENOM	HOG000195703
InParanoid	P53281
OMA	SQTKQNV
OrthoDB	EOG75MW70
BioCyc	YEAST:G3O-30842-MONOMER
NextBio	972938
Proteomes	UP000002311
Genevestigator	P53281
GO	GO:0030479 GO:0005737 GO:0005634 GO:0034316
InterPro	IPR001452
Pfam	PF00018
PRINTS	PR00452
SMART	SM00326
SUPFAM	SSF50044
PROSITE	PS50002

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	PMID:23577202	ECO:0000314			P		figure 2 show that purified Lsb1 and Lsb2 full-length proteins had an inhibitory activity on Las17-dependent actin polymerization in vitro. These results were further confirmed by measuring the KD constants of their interaction with Las17.	complete CACAO 7819
	GO:0030837	negative regulation of actin filament polymerization	PMID:23577202	ECO:0000021			P		Figure 2 gives evidence of Lsb1 and Lsb2 inhibiting Las17. Figure 4 shows Lsb1 and Lsb2 are colocalized with Las17, a protein involved in actin polymerization.	Missing: with/from CACAO 8078
part_of	GO:0005634	nucleus	PMID:14562095	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:22842922	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:22842922	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:14562095	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:11914276	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	PMID:23577202	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	PMID:23577202	ECO:0000353	physical interaction evidence used in manual assertion	SGD:S000005707	P		Seeded From UniProt	complete
involved_in	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	PMID:23577202	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0030479	actin cortical patch	PMID:23577202	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:23577202	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1900027	regulation of ruffle assembly		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1346118 PANTHER:PTN000401752	P		Seeded From UniProt	complete
involved_in	GO:0051666	actin cortical patch localization		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001037916 SGD:S000001058 SGD:S000002968	P		Seeded From UniProt	complete
involved_in	GO:0051017	actin filament bundle assembly		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001037916 SGD:S000001058	P		Seeded From UniProt	complete
enables	GO:0051015	actin filament binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001037916 SGD:S000001058	F		Seeded From UniProt	complete
enables	GO:0035091	phosphatidylinositol binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000401752 UniProtKB:Q96HL8	F		Seeded From UniProt	complete
part_of	GO:0032587	ruffle membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000401752 UniProtKB:Q96HL8	C		Seeded From UniProt	complete
part_of	GO:0030479	actin cortical patch		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001037916 SGD:S000001058 SGD:S000003368	C		Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0030479	actin cortical patch	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0008	C		Seeded From UniProt	complete
edit table

References

See Help:References for how to manage references in GONUTS.