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YEAST:HAA1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | HAA1 | |
| Protein Name(s) | Transcriptional activator HAA1 | |
| External Links | ||
| UniProt | Q12753 | |
| EMBL | U31900 Z71255 Z48951 Z49919 AY692804 BK006949 | |
| PIR | S59753 | |
| RefSeq | NP_015333.1 | |
| ProteinModelPortal | Q12753 | |
| SMR | Q12753 | |
| BioGrid | 36186 | |
| DIP | DIP-1462N | |
| IntAct | Q12753 | |
| MINT | MINT-402478 | |
| STRING | 4932.YPR008W | |
| MaxQB | Q12753 | |
| PaxDb | Q12753 | |
| EnsemblFungi | [example_ID YPR008W] | |
| GeneID | 856117 | |
| KEGG | sce:YPR008W | |
| CYGD | YPR008w | |
| SGD | S000006212 | |
| eggNOG | NOG71500 | |
| GeneTree | ENSGT00530000068810 | |
| InParanoid | Q12753 | |
| OMA | CTCGRLE | |
| OrthoDB | EOG7J9W29 | |
| BioCyc | YEAST:G3O-34170-MONOMER | |
| NextBio | 981192 | |
| Proteomes | UP000002311 | |
| Genevestigator | Q12753 | |
| GO | GO:0005634 GO:0005507 GO:0003677 GO:0000981 GO:0045944 GO:0061402 GO:0036003 GO:0006366 | |
| Gene3D | 3.90.430.10 | |
| InterPro | IPR001083 | |
| Pfam | PF00649 | |
| PRINTS | PR00617 | |
| SMART | SM00412 | |
| SUPFAM | SSF57879 | |
| PROSITE | PS01119 PS50073 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0010811 |
positive regulation of cell-substrate adhesion |
ECO:0000315 |
P |
Fig 7d: yeast not expressing yak1 or whi3 but overexpressing haa1 adhered to plate after being washed - absence of yak1 or whi3 normally leads to yeast that don't adhere to plate |
complete | |||||
|
involved_in |
GO:0061402 |
positive regulation of transcription from RNA polymerase II promoter in response to acidic pH |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0036003 |
positive regulation of transcription from RNA polymerase II promoter in response to stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061402 |
positive regulation of transcription from RNA polymerase II promoter in response to acidic pH |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_direct_input:(SGD:S000000952) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001998997 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001998997 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006878 |
cellular copper ion homeostasis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001998997 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001998997 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005507 |
copper ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001998997 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001998997 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005507 |
copper ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Tkach, JM et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat. Cell Biol. 14 966-76 PubMed GONUTS page
- ↑ Malcher, M et al. (2011) The Yak1 protein kinase lies at the center of a regulatory cascade affecting adhesive growth and stress resistance in Saccharomyces cerevisiae. Genetics 187 717-30 PubMed GONUTS page
- ↑ Swinnen, S et al. (2017) Improvement of yeast tolerance to acetic acid through Haa1 transcription factor engineering: towards the underlying mechanisms. Microb. Cell Fact. 16 7 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Keller, G et al. (2001) Haa1, a protein homologous to the copper-regulated transcription factor Ace1, is a novel transcriptional activator. J. Biol. Chem. 276 38697-702 PubMed GONUTS page
- ↑ Fernandes, AR et al. (2005) Saccharomyces cerevisiae adaptation to weak acids involves the transcription factor Haa1p and Haa1p-regulated genes. Biochem. Biophys. Res. Commun. 337 95-103 PubMed GONUTS page
- ↑ Simões, T et al. (2006) The SPI1 gene, encoding a glycosylphosphatidylinositol-anchored cell wall protein, plays a prominent role in the development of yeast resistance to lipophilic weak-acid food preservatives. Appl. Environ. Microbiol. 72 7168-75 PubMed GONUTS page
- ↑ Mira, NP et al. (2011) Identification of a DNA-binding site for the transcription factor Haa1, required for Saccharomyces cerevisiae response to acetic acid stress. Nucleic Acids Res. 39 6896-907 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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