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YEAST:GGPPS

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) BTS1
Protein Name(s) Geranylgeranyl pyrophosphate synthase

GGPP synthase GGPPSase (2E,6E)-farnesyl diphosphate synthase BET2 suppressor protein 1 Dimethylallyltranstransferase Farnesyl diphosphate synthase Farnesyltranstransferase Geranylgeranyl diphosphate synthase Geranyltranstransferase

External Links
UniProt Q12051
EMBL U39205
U31632
AY692852
BK006949
PIR S60921
RefSeq NP_015256.1
PDB 2DH4
2E8T
2E8U
2E8V
2E8W
2E8X
2E90
2E91
2E92
2E93
2E94
2E95
2Z4V
2Z4W
2Z4X
2Z4Y
2Z4Z
2Z50
2Z52
2Z78
2Z7H
2Z7I
2ZEU
2ZEV
PDBsum 2DH4
2E8T
2E8U
2E8V
2E8W
2E8X
2E90
2E91
2E92
2E93
2E94
2E95
2Z4V
2Z4W
2Z4X
2Z4Y
2Z4Z
2Z50
2Z52
2Z78
2Z7H
2Z7I
2ZEU
2ZEV
ProteinModelPortal Q12051
SMR Q12051
BioGrid 36110
DIP DIP-8889N
IntAct Q12051
MINT MINT-4504645
STRING 4932.YPL069C
BindingDB Q12051
ChEMBL CHEMBL1075251
MaxQB Q12051
PaxDb Q12051
EnsemblFungi [example_ID YPL069C]
GeneID 856036
KEGG sce:YPL069C
CYGD YPL069c
SGD S000005990
eggNOG COG0142
GeneTree ENSGT00390000010417
HOGENOM HOG000169461
InParanoid Q12051
KO K00804
OMA PEILHNG
OrthoDB EOG790G9Q
BioCyc MetaCyc:MONOMER-13701
YEAST:YPL069C-MONOMER
Reactome REACT_253879
SABIO-RK Q12051
UniPathway UPA00259
UPA00260
UPA00389
EvolutionaryTrace Q12051
NextBio 980968
PRO PR:Q12051
Proteomes UP000002311
Genevestigator Q12051
GO GO:0005737
GO:0004161
GO:0004311
GO:0004337
GO:0046872
GO:0016117
GO:0045337
GO:0033384
GO:0033386
GO:0015031
GO:0016114
Gene3D 1.10.600.10
InterPro IPR000092
IPR017446
IPR008949
PANTHER PTHR12001
Pfam PF00348
SUPFAM SSF48576
PROSITE PS00723
PS00444

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004311

farnesyltranstransferase activity

PMID:23493556[1]

ECO:0000314

F

Table S8 in the SI contains the length of the prduct produced by this enzyme. This protein is GI: 218766585. The C20 stands for geranylgeranyl diphosphate.

complete
CACAO 10248

GO:0033386

geranylgeranyl diphosphate biosynthetic process

PMID:23493556[1]

ECO:0000314

P

Table S8 in the SI contains the length of the product produced by this enzyme (GI:218766585). The C20 stands for geranylgeranyl diphosphate

complete
CACAO 10249

part_of

GO:0005739

mitochondrion

PMID:14562095[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0033386

geranylgeranyl diphosphate biosynthetic process

PMID:23493556[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004311

farnesyltranstransferase activity

PMID:23493556[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0016114

terpenoid biosynthetic process

PMID:7665600[3]

ECO:0000316

genetic interaction evidence used in manual assertion

P

Seeded From UniProt

Missing: with/from

involved_in

GO:0016114

terpenoid biosynthetic process

PMID:7665600[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016114

terpenoid biosynthetic process

PMID:7665600[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004311

farnesyltranstransferase activity

PMID:7665600[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004311

farnesyltranstransferase activity

PMID:7665600[3]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0008299

isoprenoid biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000092

P

Seeded From UniProt

complete

enables

GO:0004337

geranyltranstransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

[http://www.expasy.org/cgi-bin/nicezyme.pl?2.5.1.1 EC:2.5.1.10]

F

Seeded From UniProt

complete

enables

GO:0004311

farnesyltranstransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.5.1.29

F

Seeded From UniProt

complete

enables

GO:0004161

dimethylallyltranstransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.5.1.1

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0008299

isoprenoid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0414

P

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0045337

farnesyl diphosphate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00260

P

Seeded From UniProt

complete

involved_in

GO:0033384

geranyl diphosphate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00259

P

Seeded From UniProt

complete

involved_in

GO:0033386

geranylgeranyl diphosphate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00389

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Wallrapp, FH et al. (2013) Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc. Natl. Acad. Sci. U.S.A. 110 E1196-202 PubMed GONUTS page
  2. Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Jiang, Y et al. (1995) BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae. J. Biol. Chem. 270 21793-9 PubMed GONUTS page