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YEAST:EF3A
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | YEF3 (synonyms: EFC1, TEF3, YEF3A) | |
| Protein Name(s) | Elongation factor 3A
EF-3 EF-3A Eukaryotic elongation factor 3 eEF3 Translation elongation factor 3A Yeast elongation factor 3 | |
| External Links | ||
| UniProt | P16521 | |
| EMBL | J05197 J05583 U20865 AB018539 BK006945 | |
| PIR | S59395 | |
| RefSeq | NP_013350.1 | |
| PDB | 2IW3 2IWH 2IX3 2IX8 | |
| PDBsum | 2IW3 2IWH 2IX3 2IX8 | |
| ProteinModelPortal | P16521 | |
| SMR | P16521 | |
| BioGrid | 31517 | |
| DIP | DIP-2249N | |
| IntAct | P16521 | |
| MINT | MINT-8285353 | |
| MaxQB | P16521 | |
| PaxDb | P16521 | |
| PeptideAtlas | P16521 | |
| PRIDE | P16521 | |
| EnsemblFungi | [example_ID YLR249W] | |
| GeneID | 850951 | |
| KEGG | sce:YLR249W | |
| SGD | S000004239 | |
| eggNOG | COG0488 | |
| GeneTree | ENSGT00550000075671 | |
| HOGENOM | HOG000180957 | |
| InParanoid | P16521 | |
| KO | K03235 | |
| OMA | FPTQEEC | |
| OrthoDB | EOG7Q2NDN | |
| BioCyc | YEAST:G3O-32354-MONOMER | |
| UniPathway | UPA00345 | |
| EvolutionaryTrace | P16521 | |
| NextBio | 967419 | |
| Proteomes | UP000002311 | |
| Genevestigator | P16521 | |
| GO | GO:0010494 GO:0022626 GO:0005840 GO:0005524 GO:0016887 GO:0019843 GO:0003746 GO:0006200 GO:0006414 GO:0006415 | |
| Gene3D | 1.25.10.10 3.40.50.300 | |
| InterPro | IPR003593 IPR003439 IPR017871 IPR011989 IPR016024 IPR015688 IPR021133 IPR027417 | |
| PANTHER | PTHR19211:SF5 | |
| Pfam | PF00005 | |
| SMART | SM00382 | |
| SUPFAM | SSF48371 SSF52540 | |
| PROSITE | PS00211 PS50893 PS50077 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0010494 |
cytoplasmic stress granule |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042788 |
polysomal ribosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006469 |
negative regulation of protein kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001933 |
negative regulation of protein phosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0022626 |
cytosolic ribosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016887 |
ATPase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0010494 |
cytoplasmic stress granule |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006415 |
translational termination |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006414 |
translational elongation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000004140 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006414 |
translational elongation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005840 |
ribosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003746 |
translation elongation factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016887 |
ATPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006412 |
translation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003746 |
translation elongation factor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019843 |
rRNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006414 |
translational elongation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0251 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Jain, S et al. (2016) ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell 164 487-98 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Visweswaraiah, J et al. (2012) Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation. J. Biol. Chem. 287 37757-68 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Van Dyke, N et al. (2009) Stm1p alters the ribosome association of eukaryotic elongation factor 3 and affects translation elongation. Nucleic Acids Res. 37 6116-25 PubMed GONUTS page
- ↑ Anand, M et al. (2006) Domain and nucleotide dependence of the interaction between Saccharomyces cerevisiae translation elongation factors 3 and 1A. J. Biol. Chem. 281 32318-26 PubMed GONUTS page
- ↑ Grousl, T et al. (2013) Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae. PLoS ONE 8 e57083 PubMed GONUTS page
- ↑ Kurata, S et al. (2010) Ribosome recycling step in yeast cytoplasmic protein synthesis is catalyzed by eEF3 and ATP. Proc. Natl. Acad. Sci. U.S.A. 107 10854-9 PubMed GONUTS page
- ↑ Gontarek, RR et al. (1998) The N terminus of eukaryotic translation elongation factor 3 interacts with 18 S rRNA and 80 S ribosomes. J. Biol. Chem. 273 10249-52 PubMed GONUTS page
- ↑ Kamath, A & Chakraburtty, K (1989) Role of yeast elongation factor 3 in the elongation cycle. J. Biol. Chem. 264 15423-8 PubMed GONUTS page
