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YEAST:CTR1

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) CTR1
Protein Name(s) Copper transport protein CTR1

Copper transporter 1

External Links
UniProt P49573
EMBL U02511
U40828
AY693062
BK006949
PIR A53010
RefSeq NP_015449.1
ProteinModelPortal P49573
BioGrid 36292
DIP DIP-6447N
IntAct P49573
MINT MINT-699246
STRING 4932.YPR124W
TCDB 1.A.56.2.1
MaxQB P49573
PaxDb P49573
PeptideAtlas P49573
EnsemblFungi [example_ID YPR124W]
GeneID 856241
KEGG sce:YPR124W
CYGD YPR124w
SGD S000006328
eggNOG NOG41683
InParanoid P49573
OMA SMASMSM
OrthoDB EOG7WMCVN
BioCyc YEAST:G3O-34262-MONOMER
NextBio 981507
Proteomes UP000002311
Genevestigator P49573
GO GO:0016021
GO:0005886
GO:0015088
GO:0042802
GO:0015677
InterPro IPR007274
PANTHER PTHR12483
Pfam PF04145

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005886

plasma membrane

PMID:22842922[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:22842922[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:22842922[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

GO:0016021

integral to membrane

PMID:8293472[2]

ECO:0000314

C

Figure 3 shows an immunoelectron microscope picture of epitope tagged protein that is located in the membrane where the C-terminus side is inside the cell.

complete
CACAO 8645

part_of

GO:0016021

integral component of membrane

PMID:8293472[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0015677

copper ion import

PMID:7929270[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005375

copper ion transmembrane transporter activity

PMID:7929270[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:7929270[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006878

cellular copper ion homeostasis

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0062412
FB:FBgn0062413
MGI:MGI:1333843
MGI:MGI:1333844
PANTHER:PTN000280760
SGD:S000001218

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000196962
FB:FBgn0062411
FB:FBgn0062413
PANTHER:PTN000280760
PomBase:SPAC1142.05
PomBase:SPBC23G7.16
PomBase:SPCC1393.10
RGD:620059
SGD:S000004403
SGD:S000006328
TAIR:locus:2102752
UniProtKB:Q60EN8
UniProtKB:Q8IL79
UniProtKB:Q94EE4
dictyBase:DDB_G0287297

C

Seeded From UniProt

complete

enables

GO:0005375

copper ion transmembrane transporter activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000196962
FB:FBgn0062411
FB:FBgn0062412
FB:FBgn0062413
MGI:MGI:1333843
PANTHER:PTN000280760
PomBase:SPAC1142.05
PomBase:SPBC23G7.16
PomBase:SPCC1393.10
RGD:620059
SGD:S000001218
SGD:S000004403
SGD:S000006328
TAIR:locus:2102752
TAIR:locus:2153306
TAIR:locus:2153311
TAIR:locus:2180474
TAIR:locus:504955905
UniProtKB:Q60EN8
UniProtKB:Q94EE4

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:18467557[5]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P49573

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:16522632[6]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P49573

F

Seeded From UniProt

complete

enables

GO:0005375

copper ion transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007274

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007274

C

Seeded From UniProt

complete

involved_in

GO:0035434

copper ion transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007274

P

Seeded From UniProt

complete

involved_in

GO:0006825

copper ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0187

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Tkach, JM et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat. Cell Biol. 14 966-76 PubMed GONUTS page
  2. 2.0 2.1 Dancis, A et al. (1994) Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell 76 393-402 PubMed GONUTS page
  3. 3.0 3.1 3.2 Dancis, A et al. (1994) The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake. J. Biol. Chem. 269 25660-7 PubMed GONUTS page
  4. 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  5. Tarassov, K et al. (2008) An in vivo map of the yeast protein interactome. Science 320 1465-70 PubMed GONUTS page
  6. Singh, A et al. (2006) Assembly, activation, and trafficking of the Fet3p.Ftr1p high affinity iron permease complex in Saccharomyces cerevisiae. J. Biol. Chem. 281 13355-64 PubMed GONUTS page