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XENLA:TBX20
Contents
| Species (Taxon ID) | Xenopus laevis (African clawed frog). (8355) | |
| Gene Name(s) | tbx20 | |
| Protein Name(s) | T-box transcription factor TBX20
T-box protein 20 | |
| External Links | ||
| UniProt | Q8AXW8 | |
| EMBL | AY154394 | |
| RefSeq | NP_001079332.1 | |
| UniGene | Xl.21034 | |
| ProteinModelPortal | Q8AXW8 | |
| SMR | Q8AXW8 | |
| PRIDE | Q8AXW8 | |
| GeneID | 378656 | |
| KEGG | xla:378656 | |
| CTD | 57057 | |
| Xenbase | XB-GENE-865696 | |
| HOVERGEN | HBG067710 | |
| KO | K10185 | |
| GO | GO:0005634 GO:0003677 GO:0003700 GO:0000578 GO:0001706 GO:0048370 GO:0006351 | |
| Gene3D | 2.60.40.820 | |
| InterPro | IPR008967 IPR001699 IPR018186 | |
| PANTHER | PTHR11267 | |
| Pfam | PF00907 | |
| PRINTS | PR00937 | |
| SMART | SM00425 | |
| SUPFAM | SSF49417 | |
| PROSITE | PS01283 PS01264 PS50252 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0007507 |
heart development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048370 |
lateral mesoderm formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001706 |
endoderm formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0007507 |
heart development |
ECO:0000315 |
P |
Figure 5, Figure 7 SMAD1 activation is required for the expression of Tbx20. Tbx20 serves as a direct transcriptional target of theBMP/SMAD1 signaling pathway and is essential for cardiac development. |
complete | |||||
|
involved_in |
GO:0000578 |
embryonic axis specification |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001699 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001699 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Mandel, EM et al. (2010) The BMP pathway acts to directly regulate Tbx20 in the developing heart. Development 137 1919-29 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Stennard, FA et al. (2003) Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev. Biol. 262 206-24 PubMed GONUTS page
