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User:Thoma850

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorLACPA:K6RLY12013-04-14 16:38:17 CDTGO:0033932 1,3-alpha-L-fucosidase activity (F)PMID:21097595ECO:0000314 direct assay evidence used in manual assertion

Table 2 shows the data for the enzymatic activities of alfB in the presence of various natural fucosylated substrates. The enzymatic activity was determined by measuring the amount of fucose produced(umol) per milligram of enzyme per minute. The data shows that Alfb only causes the catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.

challenge
unacceptableLACCB:B3WBB52013-04-14 16:47:02 CDTGO:0033938 1,6-alpha-L-fucosidase activity (Table 2 shows the data for the enzymatic activities of alfA in the presence of various natural fucosylated substrates. The enzymatic activity was determined by measuring the amount of fucose produced(umol) per milligram of enzyme per minute. The data shows that AlfC only causes the catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.)PMID:21097595IDA: Inferred from Direct Assay
challenge
requireschangesHUMAN:ENOG2013-04-14 17:50:01 CDTGO:0043025 neuronal cell body (C)other:PMC3358374ECO:0000314 direct assay evidence used in manual assertion

Table 5 shows that the higher the NSE levels the greater the bad neurological outcome that was observed in patients, this was on day 0 of the study group. In addition, table 6 shows that that there was an increase in neurological worsening for patients in the study group who were administered 25.1-35ng/ml of NSE as shown in the "Yes" category. Futhermore in Figure 1, it shows that the levels of NSE between the controls and study group, in which the study group had a higher level of NSE and thus as shown in the previous tables had more severe neurological function.

challenge

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unacceptable:1
requires_changes:1
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Annotations challenged by Thoma850

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
updatedbyinstructorCasano11,
Team Its in my Jeans
PSESM:Q88A91GO:0018120 - obsolete peptidyl-arginine ADP-ribosylation (P)PMID:22013065ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
requireschangesMill2034,
Team Its Miller Time
?GO:0010629 - negative regulation of gene expression (Figure 8 shows that when a mutant for the gene is made, there is an increase in expression of the gene regulated by HDA6)PMID:22102827IMP: Inferred from Mutant Phenotype challengeC: 3
updatedbyinstructorMill2034,
Team Its Miller Time
ARATH:AB1DGO:0016042 - lipid catabolic process (P)PMID:12065405ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4

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