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User:Tatkinson

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorHUMAN:QSOX12014-02-01 19:27:55 CSTGO:0016242 negative regulation of macroautophagy (P)PMID:24475161ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2: Western blot shows that QSOX1 regulates the levels of autophagic markers p62 and LC3-II.

challenge
requireschangesCANFA:E2R5S52014-02-01 23:40:48 CSTGO:0005764 lysosome (C)PMID:24466086ECO:0000314 direct assay evidence used in manual assertion

Figure 4: DAPI nuclear stain was used to quantify the fraction of cells with a primary cilium in each sample.

challenge
unacceptableHUMAN:FLOT12014-02-02 00:48:35 CSTGO:0071806 beta-amyloid formation (P)PMID:24465508ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1: flow cytometry of knockout cells show decreased APP endocytosis.

challenge
unacceptable?2014-02-02 17:25:07 CSTGO:0042538 hyperosmotic salinity response (Figure 1: RT-PCR shows increased atCSP3 expression after exposure to a salt-rich environment.)PMID:24251108IDA: Inferred from Direct Assay
challenge
unacceptableBOVIN:TRFL2014-02-02 17:39:10 CSTGO:0009650 UV protection (P)PMID:24424315ECO:0000314 direct assay evidence used in manual assertion

Figure 1: Electrophoresis shows Lactoferrin protects DNA exposed to the Fenton reaction in a dose-dependent manner.

challenge

acceptable:0
unacceptable:3
requires_changes:1
flagged:0

Annotations challenged by Tatkinson

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Tatkinson

What do the icons mean in the status column?

assessment icons.jpg