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User:Mxb5379

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CACAO Fall 2015

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableHELPX:Q9JP552015-09-22 16:39:04 CDTGO:0098865 modification by symbiont of host bicellular tight junctions (P)PMID:24287273ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5. SEM Analysis

CagA positive H. pylori cells induced morphological changes to human gastric cells junctions.

challenge
acceptableECOLI:DNAK2015-10-19 12:38:35 CDTGO:0016234 cytoplasm (C)PMID:15866952ECO:0000314 direct assay evidence used in manual assertion

Figure 1. Shows strong Dnak chaperone system localization to the inclusion body surfaces of fusion protein VP1LAC while low levels were detected in the cytoplasm.

challenge
acceptableMYCS2:DNAK2015-10-19 13:14:07 CDTGO:0072659 protein localization to plasma membrane (P)PMID:25058675ECO:0000315 mutant phenotype evidence used in manual assertion

ATc- strain shows MalF-mCerulean protein aggregation at mid cell indicating that the DnaK chaperone system is vital for proper membrane protein localization (Figure 1D).

challenge
updatedbyinstructorECOLI:MCP22015-11-01 21:18:35 CSTGO:0051286 cell tip (C)PMID:19547746ECO:0000314 direct assay evidence used in manual assertion

Figure 2H. demonstrates that the largest clusters of the TAR chemotaxis proteins are predominately localized at the cell poles.

challenge
acceptableECOLI:CHEW2015-11-01 21:19:51 CSTGO:0051286 protein localization to plasma membrane (P)PMID:19547746ECO:0000314 direct assay evidence used in manual assertion

Figure 3C. shows that large clusters of CheW chemotaxis protein predominately assemble at the cell poles of the cellular membrane.

challenge
unacceptableECOLI:CHEY2015-11-01 21:15:54 CSTGO:0072659 protein localization to plasma membrane (P)PMID:19547746ECO:0000314 direct assay evidence used in manual assertion

Figure 3F. shows predominant CheY chemotaxis protein localization to the cellular poles of the cell membrane.

challenge

acceptable:4
unacceptable:1
requires_changes:0
flagged:0

Annotations challenged by Mxb5379

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
acceptableMxb5379,
Team PSU 2
HELPX:Q9JP55GO:0098865 - symbiont-mediated perturbation of host tight cell-cell junction (P)PMID:24287273ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2

0 annotations fixed by Mxb5379

Notes/Additional Credits

Total: 3 additional annotations

What do the icons mean in the status column?

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