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ECOLI:CHEW
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | cheW | |
| Protein Name(s) | Chemotaxis protein CheW | |
| External Links | ||
| UniProt | P0A964 | |
| EMBL | M13462 U00096 AP009048 M34669 | |
| PIR | B25195 | |
| RefSeq | NP_416401.1 YP_490149.1 | |
| PDB | 2HO9 | |
| PDBsum | 2HO9 | |
| ProteinModelPortal | P0A964 | |
| SMR | P0A964 | |
| DIP | DIP-48236N | |
| IntAct | P0A964 | |
| MINT | MINT-1283783 | |
| STRING | 511145.b1887 | |
| PaxDb | P0A964 | |
| EnsemblBacteria | AAC74957 BAA15703 | |
| GeneID | 12932044 946400 | |
| KEGG | ecj:Y75_p1863 eco:b1887 | |
| PATRIC | 32119101 | |
| EchoBASE | EB0147 | |
| EcoGene | EG10149 | |
| eggNOG | COG0835 | |
| HOGENOM | HOG000254712 | |
| InParanoid | P0A964 | |
| KO | K03408 | |
| OMA | RMICLIE | |
| OrthoDB | EOG60CWQ7 | |
| PhylomeDB | P0A964 | |
| BioCyc | EcoCyc:CHEW-MONOMER ECOL316407:JW1876-MONOMER | |
| EvolutionaryTrace | P0A964 | |
| PRO | PR:P0A964 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0A964 | |
| GO | GO:0005829 GO:0004871 GO:0006935 GO:0051649 GO:0007165 | |
| InterPro | IPR002545 | |
| Pfam | PF01584 | |
| SMART | SM00260 | |
| SUPFAM | SSF50341 | |
| PROSITE | PS50851 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
table 4, fig 2,3,4 |
complete | |||||
| GO:0051649 |
establishment of localization in cell |
ECO:0000315 |
P |
Figure 1 and Table 1. CheW expression in CheW/CheA knockout cells restored the compact clusters found in CheW+CheA+ cells. CheW/CheA knockout cells had a cap or multiple small clusters instead of a single compact cluster. |
complete | |||||
|
enables |
GO:0019904 |
protein domain specific binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0098561 |
methyl accepting chemotaxis protein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901875 |
positive regulation of post-translational protein modification |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0098561 |
methyl accepting chemotaxis protein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051649 |
establishment of localization in cell |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0051286 |
protein localization to plasma membrane |
ECO:0000314 |
P |
Figure 3C. shows that large clusters of CheW chemotaxis protein predominately assemble at the cell poles of the cellular membrane. |
complete | |||||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006935 |
chemotaxis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006935 |
chemotaxis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006935 |
chemotaxis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ridgway, HG et al. (1977) Localization of proteins controlling motility and chemotaxis in Escherichia coli. J. Bacteriol. 132 657-65 PubMed GONUTS page
- ↑ 2.0 2.1 Kentner, D et al. (2006) Determinants of chemoreceptor cluster formation in Escherichia coli. Mol. Microbiol. 61 407-17 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Mowery, P et al. (2008) Different signaling roles of two conserved residues in the cytoplasmic hairpin tip of Tsr, the Escherichia coli serine chemoreceptor. J. Bacteriol. 190 8065-74 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Li, M & Hazelbauer, GL (2005) Adaptational assistance in clusters of bacterial chemoreceptors. Mol. Microbiol. 56 1617-26 PubMed GONUTS page
- ↑ 5.0 5.1 Liu, JD & Parkinson, JS (1989) Role of CheW protein in coupling membrane receptors to the intracellular signaling system of bacterial chemotaxis. Proc. Natl. Acad. Sci. U.S.A. 86 8703-7 PubMed GONUTS page
- ↑ Greenfield, D et al. (2009) Self-organization of the Escherichia coli chemotaxis network imaged with super-resolution light microscopy. PLoS Biol. 7 e1000137 PubMed GONUTS page
- ↑ Gegner, JA & Dahlquist, FW (1991) Signal transduction in bacteria: CheW forms a reversible complex with the protein kinase CheA. Proc. Natl. Acad. Sci. U.S.A. 88 750-4 PubMed GONUTS page
