User:Garlingrk

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	BACAN:Q81YZ2	2017-04-12 10:50:53 CDT	GO:0003796 lysozyme activity (F)	PMID:21816821	ECO:0000314 direct assay evidence used in manual assertion	Figure 3A shows the bactericidal activity of lysin XlyA against B. cereus and B. subtillis. Figure 3C illustrates the residues of the XlyA catalytic domain. It is shown in this figure some structures present in the XylA catalytic domain are identical to those of PlyL, another endolysin.	challenge
unacceptable	BACAN:Q81YZ2	2017-05-06 14:45:20 CDT	GO:0003796 lysozyme activity (F)	PMID:21816821	ECO:0000247 sequence alignment evidence used in manual assertion	Figure 3B shows the sequence of the XlyA catalytic domain is similar to the catalytic domain of PlyL, another endolysin. The red boxes show XlyA contains catalytic and substrate recognition residues similar or identical to PlyL.The asterisks indicate base pair identity between XlyA and PlyL sequences. The colons indicate base pair similarity between XylA and PlyL. The high similarity and identity within the sequence alignment and secondary structure assignments of XylA and PlyL support the lysozyme function of XylA.	challenge
unacceptable	BACAN:Q81YZ2	2017-05-06 14:45:21 CDT	GO:0003796 lysozyme activity (F)	PMID:21816821	ECO:0000250 sequence similarity evidence used in manual assertion	Figure 2B shows the structural homolog of XlyA. XlyA is an endolysin. Figure 2B shows structural similarity between XlyA and another amidase lysin, PlyL.	challenge

acceptable:0
unacceptable:3
requires_changes:0
flagged:0

Annotations challenged by Garlingrk

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
acceptable	Puglisk1, Team Blue-B	BPPH2:NP	GO:0017053 - transcription repressor complex (C)	PMID:12426390	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2
acceptable	Puglisk1, Team Blue-B	BPPH2:NP	GO:0006351 - DNA-templated transcription (P)	PMID:12426390	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2
updatedbyinstructor	Robins3, Team Green-B	9CAUD:W0TUZ2	GO:0098024 - virus tail, fiber (C)	PMID:27422842	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 3

0 annotations fixed by Garlingrk

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