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User:Cmb6159

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CACAO Fall 2015

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorHUMAN:VAV32015-10-14 09:55:21 CDTGO:0001772 immunological synapse (C)PMID:15708849ECO:0000314 direct assay evidence used in manual assertion

Figure 1F. shows, using digital fluorescence microscopy, that Vav3 translocates to the plasma membrane and localizes to the immunological synapse upon T cell activation.

challenge
unacceptableHUMAN:OLR12015-11-16 18:36:44 CSTGO:0006954 inflammatory response (P)PMID:26385009ECO:0000255 match to sequence model evidence used in manual assertion

Figure 1. shows the role of LOX-1 in atherosclerosis. OxLDL binds to LOX-1 on the endothelial cell surface triggering activation of an inflammatory reaction.

challenge
unacceptableHUMAN:ID12015-11-16 23:22:49 CSTGO:0001886 endothelial cell morphogenesis (P)PMID:26476925ECO:0000314 direct assay evidence used in manual assertion

Figure 1. shows the effect of the Id1 protein on endothelial progenitor cells proliferation and migration using RT-PCR, Western blotting, and MTT assay.

challenge
updatedbyinstructorMOUSE:WNT112015-11-17 15:18:41 CSTGO:0003281 ventricular septum development (P)PMID:22569553ECO:0000316 genetic interaction evidence used in manual assertion

Figure 2 A and D: they show both the wild type and the double mutant Wnt5a -/-;Wnt11-/-. It can also be seen in figure 2 B and C that the single mutants do not fully develop the ventricular septum

challenge

acceptable:0
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Cmb6159

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