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Cacao
| GO:0030097 | hemopoiesis | PMID:23544085 | IMP: Inferred from Mutant Phenotype | P | ||||
| This annotation made on page: MOUSE:JAK2 By: Ternesch (group MichSt14A 22) on 2014-04-03 23:41:47 CDT. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Ternesch, MichSt14A 22 | 2014-04-09 15:08:05 CDT | The Go Term hemopoiesis with GO ID GO:0030097 is not specific enough to explain the data from Figure 3. The Go Term post-embryonic hemopoiesis with GO ID GO:0035166 is more accurate for the data present in Figure 3 since the tests are being conducted on post-embryonic mice. | 2 |
| Challenge | Lamarch2, MichSt14A 12 | 2014-04-08 13:23:23 CDT | The note here is word for word from the paper and does not include the figure number. I would rewrite the Note as follows: Figure 3 shows the effects of a lack of hemopoiesis in mice with a Jak2 knockout mutation. These effects include anemia, thrombocytopenia, and poikilocytosis in the blood films, abnormal splenic architecture, and increased adipose deposits in the bone marrow among others. | 2 |
| Private Assessment | Suzialeksander | 2014-05-13 16:51:45 CDT | You need to be an instructor to view these notes. | Updated by Instructor |
| Private Assessment | Shabnam | 2014-04-25 15:46:29 CDT | You need to be an instructor to view these notes. | Corrected Through Challenges ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
| Public Assessment | DanielRenfro | 2014-04-09 15:08:05 CDT | This annotation has been flagged because it has been edited since last assessment ||GO:0030097||hemopoiesis||PMID:23544085||IMP: Inferred from Mutant Phenotype||||P||B) Representative peripheral blood films from both genotypes showing the presence of anemia, thrombocytopenia, and poikilocytosis in the Jak2 cKO mice, but not the controls. (C) Histologic sections of spleen found an abnormal splenic architecture in the Jak2 cKO mice characterized by atrophied and disorganized white pulp.(D) Representative bone marrow sections from both genotypes indicating increased adipose deposits in the Jak2 cKO mice, but not the controls. (E) Representative liver sections showing diffuse centrolobular vacuolar degeneration in the Jak2 cKO tissue, but not in the control tissue. ||complete | Flagged |
| Private Assessment | Kathrynmartin | 2014-04-08 19:45:24 CDT | You need to be an instructor to view these notes. | Requires Changes ✔ Protein ✔ Publication ✔ Qualifier ✗ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
| Public Assessment | DanielRenfro | 2014-04-08 13:23:23 CDT | This annotation has been flagged because it has been edited since last assessment ||GO:0030097||hemopoiesis||PMID:23544085||IMP: Inferred from Mutant Phenotype||||P||B) Representative peripheral blood films from both genotypes showing the presence of anemia, thrombocytopenia, and poikilocytosis in the Jak2 cKO mice, but not the controls. (C) Histologic sections of spleen found an abnormal splenic architecture in the Jak2 cKO mice characterized by atrophied and disorganized white pulp.(D) Representative bone marrow sections from both genotypes indicating increased adipose deposits in the Jak2 cKO mice, but not the controls. (E) Representative liver sections showing diffuse centrolobular vacuolar degeneration in the Jak2 cKO tissue, but not in the control tissue. ||complete | Flagged |
| Private Assessment | Suzialeksander | 2014-04-07 13:55:04 CDT | You need to be an instructor to view these notes. | Requires Changes ✗ Notes |
