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GO:0045444fat cell differentiationPMID:22507984IMP: Inferred from Mutant Phenotype P
This annotation made on page: MOUSE:GRK5
By: Hayat Ahmed (group Team Helicases) on 2013-02-17 00:34:18 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeOekshyyan,
Team Pancakes at Night
2013-02-17 16:17:59 CST

A more specific GO term should have been used. Figure 4 demonstrated that GRK5 caused positive regulation of fat cell/adipose differentiation. GO Term: GO:0045600

0
ChallengeBmcrae,
Team Killing Me Smalls
2013-02-17 15:22:05 CST

Needs more information proving it affects fat cell differentiation.

0
ChallengeSmithlg,
Team Doctor Tosh
2013-02-17 13:23:06 CST

This annotation should have more explanation regarding the nature of GRK5's effect on adipose cell differentiation.

0
Public
Assessment
Bmcintosh2013-02-18 12:57:39 CST

Authors don't show the protein is specifically regulating the process of fat cell differentiation, only that it is impaired in GRK5 mutants. The notes are sufficient.

Acceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original