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GO:0070373negative regulation of ERK1 and ERK2 cascadePMID:23118896IDA: Inferred from Direct Assay P
This annotation made on page: HUMAN:RANB9
By: Courtney.kast4500 (group Team Nameless) on 2012-11-11 19:15:12 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeCbice1,
Team Smarter Who?
2012-11-18 18:03:32 CST

Figure 2 does not directly show regulation of the erk cascade. It only shows increased phosphorylation in the absence of RanBPM. The GO term is too specific; a better GO term would be something like regulation of protein phosphorylation. Additionally, the experiment shown in figure 2 uses cells transfected to express shRNAs, so IMP would be more correct for the evidence code.

1
Private
Assessment
Suzialeksander2013-06-26 15:53:28 CDTYou need to be an instructor to view these notes.Updated by Instructor
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Private
Assessment
Suzialeksander2012-12-05 15:34:39 CSTYou need to be an instructor to view these notes.Requires Changes