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GO:0043547positive regulation of GTPase activityPMID:21283621IMP: Inferred from Mutant Phenotype P
This annotation made on page: HUMAN:NDEL1
By: Oherrera (group Team That Will Beat You!!!) on 2011-10-23 13:59:24 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeOherrera,
Team That Will Beat You!!!
2011-10-30 17:27:07 CDT

Are you challenging the annotation or simply providing a suggestion for another separate annotation? I don't understand which part of the annotation you are challenging.

0
ChallengeSejal,
Team UCL-Maple Leafs
2011-10-26 13:48:58 CDT

In figure 3 Ndell enhances Dyn2 GTPase activity which is GTP hydrolysis. GTP hydrolysis simulate Dyn2 disassembly. Therefore from figure 4 another GO term for Ndell protein can be annotated to negative regulation of protein oligomerization (GO:0032460) Incubation of Ndel1 with non-assembled Dyn2 did not enhance the amount of Dyn2 recovered in the pellet (Fig. 4) Instead there was a a decrease in Dyn2 oligomerization. (IDA:experimental evidence code)

0
Private
Assessment
Sgouni2011-11-22 13:35:06 CSTYou need to be an instructor to view these notes.Acceptable