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GO:0004222metalloendopeptidase activityPMID:422IDA: Inferred from Direct Assay F
This annotation made on page: MOUSE:MMP7
By: LMoore (group Team Bulbasaur) on 2016-09-13 21:08:23 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeLMoore,
Team Bulbasaur
2016-09-20 20:26:46 CDT

Suggested GO Term: GO:0008237 This go term is for metallopeptidase activity rather than a metalloENDOpeptidase activity. It never specified that the peptide bonds that are cleaved are internal.

None, yet.
ChallengeCSears,
Team Pik-Achoo!
2016-09-20 19:51:00 CDT

PMID:15297466

2
Public
Assessment
Suzialeksander2016-10-04 13:38:13 CDT

This is a really good assay for this term. However, they seem to have purchased this MMP-7 (not mouse) instead of isolating it themselves, so it's not really going to be acceptable for an annotation. Maybe find a paper where they did a similar assay but isolated the protein in the lab? (Judging off PMID:15297466 )

Unacceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
Suzialeksander2016-09-28 15:44:05 CDT

PMID:15297466 is the right paper. Checking specificity of GO.

Flagged
Publication