GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:0032689 | negative regulation of interferon-gamma production | PMID:19265145 | IDA: Inferred from Direct Assay | P | ||||
| This annotation made on page: MYCTU:ESXA By: Jonathan.Yuen (group Team Not Very Creative) on 2016-04-06 08:19:09 CDT. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Heidi.Larson.1, Team Grapes of Staph | 2016-04-04 19:53:34 CDT | Because the paper specifically mentions that the IFN-y "secretion" is reduced, I would use the child term GO:1902714, which is for the negative regulation of interferon-gamma "secretion." This term (GO:1902714) has no children terms, so it is the most specific you can get. | 0 |
| Challenge | Heidi.Larson.1, Team Grapes of Staph | 2016-04-04 19:48:43 CDT | For your note, please be more specific about what figure 4B shows. It appears that Figure 4B shows that increasing concentrations of ESAT-6 reduces IFN-y production by human T cells. | 0 |
| Private Assessment | Suzialeksander | 2016-04-06 20:27:42 CDT | You need to be an instructor to view these notes. | Unacceptable ✗ Unique/Original |
| Public Assessment | Suzialeksander | 2016-04-06 19:56:09 CDT | From the original judge: GO term: wrong, I think you can only get one GO term out of this paper? Basically, the authors noticed that IFN-g secretion decreases when you add ESAT-6 to white blood cells and tried to explain this. Everything ultimately boils down to: ESAT-6 interrupts T cell activation somewhere downstream of ZAP70 phosphorylation and somewhere upstream of IFN-g transcription | Requires Changes ✗ Go term ✗ Notes |
| Public Assessment | DanielRenfro | 2016-04-04 19:53:34 CDT | This annotation has been flagged because it has been challenged since last assessment | Flagged |
| Public Assessment | DanielRenfro | 2016-04-04 19:48:43 CDT | This annotation has been flagged because it has been challenged since last assessment | Flagged |
| Private Assessment | Suzialeksander | 2016-04-01 09:42:49 CDT | You need to be an instructor to view these notes. | Requires Changes ✔ Protein ✔ Publication ✔ Qualifier ✗ Go term ✔ Evidence ✔ With/From ✗ Notes |
| Private Assessment | Min.lorna | 2016-03-29 19:42:36 CDT | You need to be an instructor to view these notes. | Flagged |
