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GO:0010629negative regulation of gene expressionPMID:25518932IMP: Inferred from Mutant Phenotype P
This annotation made on page: HUMAN:ITCH
By: Yeyuan (group Team Bob Ross) on 2015-09-22 17:53:52 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeMadstidham1,
Team G-nomes
2015-11-03 21:11:41 CST

Figure 3A-B should be used with the GO term GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process

8
ChallengeMadstidham1,
Team G-nomes
2015-11-03 18:38:16 CST

GO:0000122 negative regulation of transcription from RNA polymerase II promoter

0
ChallengeAnnie luca,
Team You cannot B. cereus
2015-10-06 20:09:04 CDT

The GO term should change to GO:0016458 gene silencing.

0
ChallengeMadstidham1,
Team G-nomes
2015-10-06 18:48:43 CDT

All are correct except the GO term should be: GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway

(I would use 3 A and B to show this)

0
ChallengeMadstidham1,
Team G-nomes
2015-10-06 18:47:07 CDT

the gene should be Q8C863 (ITCH_MOUSE)

0
ChallengeAnnie luca,
Team You cannot B. cereus
2015-09-22 20:28:50 CDT

Figure 3B. The assay conditions specify that exists an OVEREXPRESSION of ITCH, and as a consequence inhibits the protein expression of Smad7. It is not data than can support "a negative regulation of gene expression" of ITCH under regular conditions.

0
Private
Assessment
Suzialeksander2015-12-08 15:53:03 CSTYou need to be an instructor to view these notes.Unacceptable
Unique/Original
Private
Assessment
Suzialeksander2015-11-05 15:29:14 CSTYou need to be an instructor to view these notes.Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2015-11-03 21:11:41 CST

This annotation has been flagged because it has been challenged since last assessment

Flagged
Public
Assessment
DanielRenfro2015-11-03 18:38:16 CST

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Suzialeksander2015-10-15 14:17:47 CDTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
DanielRenfro2015-10-06 20:09:05 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Public
Assessment
DanielRenfro2015-10-06 18:48:43 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Public
Assessment
DanielRenfro2015-10-06 18:47:07 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Suzialeksander2015-09-30 14:29:58 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original