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Cacao

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GO:0015307drug:proton antiporter activityPMID:20573661IDA: Inferred from Direct Assay F
This annotation made on page: ACIBY:B0V737
By: Anjali (group Team Swanson) on 2015-02-18 20:26:44 CST.



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Team Swanson0




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Private
Assessment		Suzialeksander2015-03-11 14:05:48 CDTYou need to be an instructor to view these notes.Requires Changes
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Public
Assessment		DanielRenfro2015-03-09 23:34:38 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0015307 drug:proton antiporter activity PMID:20573661 IMP: Inferred from Mutant Phenotype F Figure 1 shows that AmvA confers resistance in E.coli cells carrying the A.baumanii AmvA to antibiotics. Addition of the proton motive force decoupler CCCP renders the bacteria susceptible again. Figure 2 shows that A.baumanii and E.coli carrying the A.baumanii amva gene accumulate ethidium bromide and acriflavine more slowly compared to wild-type E.coli. Once CCCP is added, the concentration of these two increases sharply, implying a proton motive force driven transport of the drugs out of the cell prior to addition of the CCCP. complete
CACAO 10686
on ACIBY:B0V737
Flagged
Private
Assessment		Suzialeksander2015-03-05 16:39:35 CSTYou need to be an instructor to view these notes.Requires Changes
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✔ With/From
✔ Unique/Original


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