STAEP:GSEA

Species (Taxon ID)	Staphylococcus epidermidis. (1282)
Gene Name(s)	gseA (synonyms: esp)
Protein Name(s)	Glutamyl endopeptidase Glutamic acid-specific protease GluSE
External Links
UniProt	P0C0Q1
EMBL	AB096695 AJ305145
RefSeq	WP_001829860.1
ProteinModelPortal	P0C0Q1
SMR	P0C0Q1
STRING	176279.SERP1397
KEGG	seps:DP17_458
KO	K01318
BRENDA	3.4.21.19
GO	GO:0005576 GO:0004252 GO:0009405
InterPro	IPR009003 IPR008256 IPR008353 IPR000126
PRINTS	PR01774 PR00839
SUPFAM	SSF50494
PROSITE	PS00673

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0008233	peptidase activity	PMID:23970550	ECO:0000315			F		Figure 1C. Esp activity assay was performed and enzymatic activity was measured. Figure 1D. purified pro-Esp, Esp, or EspS235A was incubated with S. aureus Newman during assembly of biofilms and graph shoes considerable reduction on biofilm formation for Esp sample. In conclusion, purified, recombinant Esp displays protease activity, inhibiting S. aureus biofilm formation and cleaving Atl	complete CACAO 11144
	GO:0009405	pathogenesis	PMID:23970550	ECO:0000315			P		Figure 6. Shows that Esp blocks the release of extracellular DNA during biofilm formation	complete CACAO 11148
enables	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008353	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000126 InterPro:IPR008256 InterPro:IPR008353	P		Seeded From UniProt	complete
enables	GO:0008236	serine-type peptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000126 InterPro:IPR008256	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0843	P		Seeded From UniProt	complete
enables	GO:0008236	serine-type peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0720	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
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References

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