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SCHPO:SGO2
Contents
| Species (Taxon ID) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812) | |
| Gene Name(s) | sgo2 | |
| Protein Name(s) | Shugoshin-2 | |
| External Links | ||
| UniProt | O13734 | |
| EMBL | CU329670 AB027892 | |
| PIR | T37714 | |
| RefSeq | NP_594301.1 | |
| BioGrid | 279237 | |
| DIP | DIP-59226N | |
| IntAct | O13734 | |
| STRING | 4896.SPAC15A10.15.1 | |
| iPTMnet | O13734 | |
| MaxQB | O13734 | |
| PaxDb | O13734 | |
| PRIDE | O13734 | |
| EnsemblFungi | SPAC15A10.15.1 | |
| GeneID | 2542788 | |
| KEGG | spo:SPAC15A10.15 | |
| EuPathDB | FungiDB:SPAC15A10.15 | |
| PomBase | SPAC15A10.15 | |
| InParanoid | O13734 | |
| OMA | KMRRDFN | |
| PhylomeDB | O13734 | |
| PRO | PR:O13734 | |
| Proteomes | UP000002485 | |
| GO | GO:0000775 GO:0000781 GO:0000778 GO:0000780 GO:0005737 GO:0072687 GO:0072686 GO:0005720 GO:0005634 GO:1990421 GO:0031933 GO:0051301 GO:0072356 GO:0045143 GO:0000070 | |
| InterPro | IPR038889 IPR011515 IPR011516 | |
| PANTHER | PTHR21577 | |
| Pfam | PF07557 PF07558 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:1990421 |
subtelomeric heterochromatin |
ECO:0000314 |
C |
ChIP–chip analysis of the genome-wide distribution of Sgo2-Flag in logarithmically growing wt cells. It is noteworthy that the probes used in the tiling array did not encompass regions outside the rDNA repeats on chromosome 3. (c) Magnification of the ChIP–chip data for the subtelomeric regions shown in b. |
complete | |||||
| GO:1903467 |
negative regulation of mitotic DNA replication initiation |
ECO:0000315 |
P |
Figure 7 |
complete | |||||
|
part_of |
GO:1990421 |
subtelomeric heterochromatin |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0000085) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0072687 |
meiotic spindle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0072686 |
mitotic spindle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0072356 |
chromosome passenger complex localization to kinetochore |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045143 |
homologous chromosome segregation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031933 |
telomeric heterochromatin |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005720 |
nuclear heterochromatin |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000781 |
chromosome, telomeric region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0000085) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000780 |
condensed nuclear chromosome, centromeric region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000778 |
condensed nuclear chromosome kinetochore |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000775 |
chromosome, centromeric region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000070 |
mitotic sister chromatid segregation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000775 |
chromosome, centromeric region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045132 |
meiotic chromosome segregation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051321 |
meiotic cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000775 |
chromosome, centromeric region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007059 |
chromosome segregation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051301 |
cell division |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005694 |
chromosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Tashiro, S et al. (2016) Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing. Nat Commun 7 10393 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Kawashima, SA et al. (2010) Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin. Science 327 172-7 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Kitajima, TS et al. (2004) The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis. Nature 427 510-7 PubMed GONUTS page
- ↑ 4.0 4.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
- ↑ Rabitsch, KP et al. (2004) Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II. Curr. Biol. 14 287-301 PubMed GONUTS page
c
- GO:0007049 ! cell cycle
- GO:0051301 ! cell division
- GO:0005694 ! chromosome
- GO:0000781 ! chromosome, telomeric region
- GO:0000775 ! chromosome, centromeric region
- GO:0072356 ! chromosome passenger complex localization to kinetochore
- GO:0007059 ! chromosome segregation
- GO:0000778 ! condensed nuclear chromosome kinetochore
- GO:0000780 ! condensed nuclear chromosome, centromeric region
- GO:0005737 ! cytoplasm
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