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SCHPO:SET1
Contents
| Species (Taxon ID) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812) | |
| Gene Name(s) | set1 (ECO:0000312 with EMBL:CAB41652.1) (synonyms: kmt2) | |
| Protein Name(s) | Histone-lysine N-methyltransferase, H3 lysine-4 specific
COMPASS component set1 Lysine N-methyltransferase 2 SET domain-containing protein 1 Set1 complex component set1 Set1C component set1 Spset1 | |
| External Links | ||
| UniProt | Q9Y7R4 | |
| EMBL | CU329672 | |
| PIR | T41282 | |
| RefSeq | NP_587812.1 | |
| ProteinModelPortal | Q9Y7R4 | |
| SMR | Q9Y7R4 | |
| BioGrid | 275345 | |
| ELM | Q9Y7R4 | |
| IntAct | Q9Y7R4 | |
| STRING | 4896.SPCC306.04c.1 | |
| iPTMnet | Q9Y7R4 | |
| MaxQB | Q9Y7R4 | |
| PaxDb | Q9Y7R4 | |
| PRIDE | Q9Y7R4 | |
| EnsemblFungi | SPCC306.04c.1 | |
| GeneID | 2538762 | |
| KEGG | spo:SPCC306.04c | |
| EuPathDB | FungiDB:SPCC306.04c | |
| PomBase | SPCC306.04c | |
| InParanoid | Q9Y7R4 | |
| KO | K11422 | |
| OMA | PSCTAKI | |
| PhylomeDB | Q9Y7R4 | |
| Reactome | R-SPO-3214841 | |
| PRO | PR:Q9Y7R4 | |
| Proteomes | UP000002485 | |
| GO | GO:0005737 GO:0000790 GO:0048188 GO:0042800 GO:0003723 GO:0070869 GO:0051568 | |
| Gene3D | 3.30.70.330 | |
| InterPro | IPR024657 IPR012677 IPR003616 IPR035979 IPR000504 IPR017111 IPR024636 IPR001214 | |
| PANTHER | PTHR22884:SF462 | |
| Pfam | PF11764 PF00076 PF00856 PF11767 | |
| PIRSF | PIRSF037104 | |
| SMART | SM01291 SM00508 SM00360 SM00317 | |
| SUPFAM | SSF54928 | |
| PROSITE | PS50868 PS50102 PS51572 PS50280 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0070869 |
heterochromatin assembly involved in chromatin silencing |
ECO:0000305 |
curator inference used in manual assertion |
GO:0048188 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051568 |
histone H3-K4 methylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051568 |
histone H3-K4 methylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051568 |
histone H3-K4 methylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0048188 |
Set1C/COMPASS complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042800 |
histone methyltransferase activity (H3-K4 specific) |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042800 |
histone methyltransferase activity (H3-K4 specific) |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_direct_input:(PomBase:SPBC8D2.04) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042800 |
histone methyltransferase activity (H3-K4 specific) |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_direct_input:(PomBase:SPBC1105.11c) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042800 |
histone methyltransferase activity (H3-K4 specific) |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_direct_input:(PomBase:SPAC1834.04) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000255 |
match to sequence model evidence used in manual assertion |
Pfam:PF00076 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000790 |
nuclear chromatin |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0018024 |
histone-lysine N-methyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034968 |
histone lysine methylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0048188 |
Set1C/COMPASS complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0018024 |
histone-lysine N-methyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032259 |
methylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005694 |
chromosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008168 |
methyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wang, W et al. (2014) [Ash2, a subunit of histone H3K4 methyltransferase complex, is involved in the sporulation in Schizosaccharomyces pombe]. Yi Chuan 36 943-51 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Kanoh, J et al. (2003) The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway. J. Mol. Biol. 326 1081-94 PubMed GONUTS page
- ↑ 3.0 3.1 Noma, K & Grewal, SI (2002) Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast. Proc. Natl. Acad. Sci. U.S.A. 99 Suppl 4 16438-45 PubMed GONUTS page
- ↑ Roguev, A et al. (2003) High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. J. Biol. Chem. 278 8487-93 PubMed GONUTS page
- ↑ Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
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