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SCHPO:CBF11

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) cbf11
Protein Name(s) Transcription factor cbf11

C-promoter element-binding factor-like protein 11

External Links
UniProt O74954
EMBL CU329672
PIR T41565
RefSeq NP_587779.1
ProteinModelPortal O74954
BioGrid 276121
STRING 4896.SPCC736.08.1
iPTMnet O74954
MaxQB O74954
PaxDb O74954
PRIDE O74954
EnsemblFungi SPCC736.08.1
GeneID 2539560
KEGG spo:SPCC736.08
EuPathDB FungiDB:SPCC736.08
PomBase SPCC736.08
InParanoid O74954
OMA DSREFGC
PhylomeDB O74954
PRO PR:O74954
Proteomes UP000002485
GO GO:0005829
GO:0000790
GO:0005634
GO:0005667
GO:0001228
GO:0003700
GO:0000978
GO:0000977
GO:0043565
GO:0007155
GO:0045944
GO:0019216
Gene3D 2.60.40.1450
InterPro IPR015350
IPR036358
IPR040159
IPR008967
IPR015351
IPR037095
PANTHER PTHR10665
Pfam PF09270
PF09271
SMART SM01268
SM01267
SUPFAM SSF110217
SSF49417

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003700

sequence-specific DNA binding transcription factor activity

PMID:23555033[1]

ECO:0000315

F

Figure 3A through Figure 3G shows Cbf11 regulates gene expression, but requires DNA binding to do so.

complete
CACAO 8037

enables

GO:0003700

DNA-binding transcription factor activity

PMID:23555033[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:27687771[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:23555033[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:19101542[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:26366556[4]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001839)

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:19101542[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0019216

regulation of lipid metabolic process

PMID:26366556[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:16823372[5]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:16823372[5]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:19101542[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:27687771[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_direct_input:(PomBase:SPCC1235.02)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:27687771[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_direct_input:(PomBase:SPAC56E4.04c)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:27687771[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_direct_input:(PomBase:SPAC1B3.16c)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:26366556[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_regulation_target:(PomBase:SPCC1450.16c)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:26366556[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_regulation_target:(PomBase:SPCC1281.06c)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:26366556[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_regulation_target:(PomBase:SPBP4H10.11c)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:26366556[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_regulation_target:(PomBase:SPBC18H10.02)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:26366556[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_regulation_target:(PomBase:SPAC56E4.04c)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:26366556[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_regulation_target:(PomBase:SPAC22A12.06c)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:23555033[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:23555033[1]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001839)

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:21858190[6]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001839)

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:19101542[3]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001839)

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:27687771[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001839)

Seeded From UniProt

complete

part_of

GO:0000790

nuclear chromatin

PMID:26366556[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96522
PANTHER:PTN000071433
PomBase:SPCC736.08
UniProtKB:Q06330
WB:WBGene00002245

F

Seeded From UniProt

complete

part_of

GO:0005667

transcription factor complex

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1196616
MGI:MGI:96522
PANTHER:PTN000071433

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004837
MGI:MGI:1196616
MGI:MGI:96522
PANTHER:PTN000071433
PomBase:SPCC1223.13
PomBase:SPCC736.08
RGD:1310557
UniProtKB:Q06330
WB:WBGene00002245

C

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015350

F

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR040159

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015351
InterPro:IPR037095

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008967
InterPro:IPR015351
InterPro:IPR037095

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015351
InterPro:IPR037095

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008967
InterPro:IPR015351
InterPro:IPR037095

P

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015350
InterPro:IPR040159

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Oravcová, M et al. (2013) Fission yeast CSL proteins function as transcription factors. PLoS ONE 8 e59435 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Převorovský, M et al. (2016) CSL protein regulates transcription of genes required to prevent catastrophic mitosis in fission yeast. Cell Cycle 15 3082-3093 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Prevorovský, M et al. (2009) Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division. Exp. Cell Res. 315 1533-47 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Převorovský, M et al. (2015) Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles. PLoS ONE 10 e0137820 PubMed GONUTS page
  5. 5.0 5.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  6. Převorovský, M et al. (2011) N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast. PLoS ONE 6 e23650 PubMed GONUTS page
  7. 7.0 7.1 7.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page