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SCHPO:CBF11

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) cbf11
Protein Name(s) Transcription factor cbf11

C-promoter element-binding factor-like protein 11

External Links
UniProt O74954
EMBL CU329672
PIR T41565
RefSeq NP_587779.1
ProteinModelPortal O74954
STRING 4896.SPCC736.08-1
EnsemblFungi SPCC736.08.1
GeneID 2539560
KEGG spo:SPCC736.08
PomBase SPCC736.08
eggNOG NOG295376
KO K06053
OrthoDB EOG4SN4Z3
NextBio 20800720
GO GO:0005829
GO:0005634
GO:0000978
GO:0000982
GO:0007155
GO:0022408
GO:0010812
GO:0045944
GO:0032955
GO:0010590
GO:0051783
Gene3D 2.60.40.1450
InterPro IPR015350
IPR015351
IPR008967
Pfam PF09270
PF09271
SUPFAM SSF110217
SSF49417

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000978

RNA polymerase II core promoter proximal region sequence-specific DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015350

F

Seeded From UniProt

GO:0000978

RNA polymerase II core promoter proximal region sequence-specific DNA binding

PMID:19101542[1]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0000982

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015350

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015351

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

Seeded From UniProt

GO:0003700

sequence-specific DNA binding transcription factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008967
InterPro:IPR015351

F

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015350
InterPro:IPR015351

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

GO:0005634

nucleus

PMID:16823372[2]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005634

nucleus

PMID:19101542[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

GO:0005829

cytosol

PMID:16823372[2]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0006351

transcription, DNA-dependent

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008967
InterPro:IPR015350
InterPro:IPR015351

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

Seeded From UniProt

GO:0007155

cell adhesion

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

Seeded From UniProt

GO:0010590

regulation of cytokinetic cell separation

PMID:19101542[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0010812

negative regulation of cell-substrate adhesion

PMID:19101542[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0022408

negative regulation of cell-cell adhesion

PMID:19101542[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0032955

regulation of barrier septum assembly

PMID:19101542[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0043565

sequence-specific DNA binding

PMID:19101542[1]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0043565

sequence-specific DNA binding

PMID:21858190[3]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

PMID:19101542[1]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0051783

regulation of nuclear division

PMID:19101542[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0003700

sequence-specific DNA binding transcription factor activity

PMID:23555033[4]

IMP: Inferred from Mutant Phenotype

F

Figure 3A through Figure 3G shows Cbf11 regulates gene expression, but requires DNA binding to do so.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Prevorovský, M et al. (2009) Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division. Exp. Cell Res. 315 1533-47 PubMed GONUTS page
  2. 2.0 2.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  3. Převorovský, M et al. (2011) N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast. PLoS ONE 6 e23650 PubMed GONUTS page
  4. Oravcová, M et al. (2013) Fission yeast CSL proteins function as transcription factors. PLoS ONE 8 e59435 PubMed GONUTS page