RICCO:RICI

Species (Taxon ID)	Ricinus communis (Castor bean). (3988)
Gene Name(s)	No Information Provided.
Protein Name(s)	Ricin Ricin A chain rRNA N-glycosidase Linker peptide Ricin B chain
External Links
UniProt	P02879
EMBL	X03179 X52908 X02388
PIR	A24041
RefSeq	XP_002534649.1
PDB	1BR5 1BR6 1IFS 1IFT 1IFU 1IL3 1IL4 1IL5 1IL9 1J1M 1OBS 1OBT 1RTC 1UQ4 1UQ5 2AAI 2P8N 2PJO 2R2X 2R3D 2VC3 2VC4 3BJG 3EJ5 3HIO 3LC9 3MK9 3PX8 3PX9 3RTI 3RTJ 3SRP 4ESI 4HUO 4HUP 4HV3 4HV7 4IMV 4KUC 4LGP 4LGR 4LGS 4LHJ 4LHQ 4MX1 4MX5
PDBsum	1BR5 1BR6 1IFS 1IFT 1IFU 1IL3 1IL4 1IL5 1IL9 1J1M 1OBS 1OBT 1RTC 1UQ4 1UQ5 2AAI 2P8N 2PJO 2R2X 2R3D 2VC3 2VC4 3BJG 3EJ5 3HIO 3LC9 3MK9 3PX8 3PX9 3RTI 3RTJ 3SRP 4ESI 4HUO 4HUP 4HV3 4HV7 4IMV 4KUC 4LGP 4LGR 4LGS 4LHJ 4LHQ 4MX1 4MX5
ProteinModelPortal	P02879
SMR	P02879
BioGrid	1022023
DIP	DIP-46421N
IntAct	P02879
MINT	MINT-8391414
BindingDB	P02879
ChEMBL	CHEMBL4756
Allergome	2803
CAZy	CBM13
UniCarbKB	P02879
GeneID	8287993
KEGG	rcu:RCOM_2159910
BRENDA	3.2.2.22
EvolutionaryTrace	P02879
GO	GO:0005783 GO:0030246 GO:0000166 GO:0030598 GO:0006952 GO:0017148
Gene3D	3.40.420.10 4.10.470.10
InterPro	IPR001574 IPR017988 IPR016138 IPR016139 IPR017989 IPR000772
Pfam	PF00652 PF00161
PRINTS	PR00396
SMART	SM00458
SUPFAM	SSF50370 SSF56371
PROSITE	PS50231 PS00275

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0031640	killing of cells of other organism	PMID:22069759	ECO:0000314			P		Ricin toxin binds to the ribosome thereby blocks protein synthesis and cause cell death (Apoptosis). Figure 1 shows a drastic decrease in cell viability with increasing concentration of Ricin.	complete CACAO 3764
	GO:0006915	apoptotic process	PMID:11324424	ECO:0000314			P		Figure 4.	complete CACAO 4509
	GO:0031640	killing of cells of other organism	PMID:11324424	ECO:0000314			P		Figure 4.	complete CACAO 4601
involved_in	GO:0031640	killing of cells of other organism	PMID:22069759	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0090729	P		Seeded From UniProt	complete
involved_in	GO:0017148	negative regulation of translation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001574 InterPro:IPR016138 InterPro:IPR017988 InterPro:IPR036041	P		Seeded From UniProt	complete
enables	GO:0030598	rRNA N-glycosylase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001574 InterPro:IPR016138 InterPro:IPR017988 InterPro:IPR017989 InterPro:IPR036041	F		Seeded From UniProt	complete
enables	GO:0030598	rRNA N-glycosylase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.2.2.22	F		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	PMID:11870775	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0017148	negative regulation of translation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0652	P		Seeded From UniProt	complete
involved_in	GO:0006952	defense response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0611	P		Seeded From UniProt	complete
enables	GO:0090729	toxin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0800	F		Seeded From UniProt	complete
enables	GO:0030246	carbohydrate binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0430	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
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References

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