RAT:VANG2

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Vangl2 (ECO:0000312 with RGD:1309442)
Protein Name(s)	Vang-like protein 2 Van Gogh-like protein 2
External Links
UniProt	P84889
EMBL	AABR03084676
RefSeq	NP_001099439.1 XP_006250338.1 XP_006250339.1
UniGene	Rn.198958
ProteinModelPortal	P84889
BioGrid	252835
IntAct	P84889
MINT	MINT-8416720
STRING	10116.ENSRNOP00000006849
PhosphoSite	P84889
PaxDb	P84889
PRIDE	P84889
Ensembl	ENSRNOT00000006849
GeneID	289229
KEGG	rno:289229
UCSC	RGD:1309442
CTD	57216
RGD	1309442
eggNOG	NOG268286
GeneTree	ENSGT00390000012496
HOGENOM	HOG000230590
HOVERGEN	HBG058215
InParanoid	P84889
KO	K04510
OMA	MWHRESD
OrthoDB	EOG7MSMNR
PhylomeDB	P84889
TreeFam	TF313467
Reactome	REACT_198389 REACT_198391
NextBio	629422
PRO	PR:P84889
Proteomes	UP000002494
Genevestigator	P84889
GO	GO:0016324 GO:0016323 GO:0060187 GO:0005911 GO:0030134 GO:0016021 GO:0016328 GO:0001725 GO:0009952 GO:0045176 GO:0035787 GO:0090103 GO:0060028 GO:0022007 GO:0048546 GO:0048105 GO:0090177 GO:0045197 GO:0032835 GO:0001942 GO:0001947 GO:0060122 GO:0060993 GO:0060490 GO:0003149 GO:0003150 GO:0035058 GO:0060488 GO:0003402 GO:0061346 GO:0090179 GO:0060489 GO:0043507 GO:0036342 GO:0032956 GO:0030111 GO:0007266 GO:0048103 GO:0035019 GO:0042060
InterPro	IPR009539
PANTHER	PTHR20886
Pfam	PF06638
PIRSF	PIRSF007991

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
Colocalizes with	GO:0016021	integral to membrane	PMID:22363783	ECO:0000315			C		Figure one: Illustrates the effects of the mutant phenotype in the vangl2 gene.	complete
involved_in	GO:0008150	biological_process	GO_REF:0000015	ECO:0000307	no biological data found used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005575	cellular_component	GO_REF:0000015	ECO:0000307	no biological data found used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003674	molecular_function	GO_REF:0000015	ECO:0000307	no biological data found used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:1905515	non-motile cilium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:1904938	planar cell polarity pathway involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0090179	planar cell polarity pathway involved in neural tube closure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0090177	establishment of planar polarity involved in neural tube closure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0090175	regulation of establishment of planar polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0090103	cochlea morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0090102	cochlea development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
part_of	GO:0071944	cell periphery	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
involved_in	GO:0061346	planar cell polarity pathway involved in heart morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060993	kidney morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060490	lateral sprouting involved in lung morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
part_of	GO:0060187	cell pole	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
involved_in	GO:0060122	inner ear receptor cell stereocilium organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060119	inner ear receptor cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060029	convergent extension involved in organogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0060028	convergent extension involved in axis elongation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0048546	digestive tract morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0048105	establishment of body hair planar orientation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0048103	somatic stem cell division	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0045176	apical protein localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0043507	positive regulation of JUN kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0042060	wound healing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0036515	serotonergic neuron axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0036514	dopaminergic neuron axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0036342	post-anal tail morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0035787	cell migration involved in kidney development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0035567	non-canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0035019	somatic stem cell population maintenance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0032956	regulation of actin cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0032835	glomerulus development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
part_of	GO:0030134	COPII-coated ER to Golgi transport vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
involved_in	GO:0030111	regulation of Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0022007	convergent extension involved in neural plate elongation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
part_of	GO:0016328	lateral plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
involved_in	GO:0015012	heparan sulfate proteoglycan biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0009952	anterior/posterior pattern specification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0007266	Rho protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
part_of	GO:0005911	cell-cell junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
involved_in	GO:0003402	planar cell polarity pathway involved in axis elongation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0003150	muscular septum morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0003149	membranous septum morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0001947	heart looping	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0001942	hair follicle development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0001843	neural tube closure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
involved_in	GO:0001736	establishment of planar polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	P		Seeded From UniProt	complete
part_of	GO:0001725	stress fiber	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q91ZD4 ensembl:ENSMUSP00000106894	C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009539	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009539	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
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References

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