GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

RAT:UD12

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Ugt1a2 (synonyms: Ugt1)
Protein Name(s) UDP-glucuronosyltransferase 1-2

UDPGT 1-2 UGT1*2 UGT1-02 UGT1.2 B2 Bilirubin-specific UDPGT UDP-glucuronosyltransferase 1A2 UGT1A2

External Links
UniProt P20720
EMBL M34007
D38066
PIR A35343
UniGene Rn.26489
ProteinModelPortal P20720
CAZy GT1
PRIDE P20720
RGD 1549741
HOGENOM HOG000220832
HOVERGEN HBG004033
InParanoid P20720
BRENDA 2.4.1.17
Proteomes UP000002494
Genevestigator P20720
GO GO:0005789
GO:0016021
GO:0015020
GO:0001889
GO:0031100
GO:0014070
InterPro IPR002213
PANTHER PTHR11926
Pfam PF00201
PROSITE PS00375

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0031100

animal organ regeneration

PMID:16222444[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0014070

response to organic cyclic compound

PMID:11854140[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001889

liver development

PMID:18938141[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0052697

xenobiotic glucuronidation

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000230517
RGD:3935
UniProtKB:O60656
UniProtKB:P22309
UniProtKB:P35503
UniProtKB:Q9HAW7
UniProtKB:Q9HAW9

P

Seeded From UniProt

complete

involved_in

GO:0052696

flavonoid glucuronidation

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000230517
RGD:3935
UniProtKB:O60656
UniProtKB:P22309
UniProtKB:P35503
UniProtKB:Q9HAW7
UniProtKB:Q9HAW9

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000230403
RGD:3935
RGD:620895
RGD:620949
RGD:708541

C

Seeded From UniProt

complete

enables

GO:0008194

UDP-glycosyltransferase activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2145969
MGI:MGI:2146055
PANTHER:PTN000230403
TAIR:locus:2028190
TAIR:locus:2040570
TAIR:locus:2093089
TAIR:locus:2093104
TAIR:locus:2142654
TAIR:locus:2198791
UniProtKB:Q3SY77
UniProtKB:Q6NUS8
UniProtKB:Q7XT97
UniProtKB:Q9M156

F

Seeded From UniProt

complete

enables

GO:0016758

transferase activity, transferring hexosyl groups

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002213

F

Seeded From UniProt

complete

enables

GO:0015020

glucuronosyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.4.1.17

F

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0492
UniProtKB-SubCell:SL-0166

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Tian, H et al. (2005) Activity and expression of various isoforms of uridine diphosphate glucuronosyltransferase are differentially regulated during hepatic regeneration in rats. Pharm. Res. 22 2007-15 PubMed GONUTS page
  2. Vansell, NR & Klaassen, CD (2002) Increase in rat liver UDP-glucuronosyltransferase mRNA by microsomal enzyme inducers that enhance thyroid hormone glucuronidation. Drug Metab. Dispos. 30 240-6 PubMed GONUTS page
  3. Kishi, M et al. (2008) Ontogenic isoform switching of UDP-glucuronosyltransferase family 1 in rat liver. Biochem. Biophys. Res. Commun. 377 815-9 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page