RAT:P2RY1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	P2ry1
Protein Name(s)	P2Y purinoceptor 1 P2Y1 ATP receptor Purinergic receptor
External Links
UniProt	P49651
EMBL	U22830
RefSeq	NP_036932.1
UniGene	Rn.10217
ProteinModelPortal	P49651
MINT	MINT-242266
STRING	10116.ENSRNOP00000019304
BindingDB	P49651
ChEMBL	CHEMBL2497
GuidetoPHARMACOLOGY	323
PhosphoSite	P49651
PRIDE	P49651
Ensembl	ENSRNOT00000019305
GeneID	25265
KEGG	rno:25265
UCSC	RGD:3242
CTD	5028
RGD	3242
eggNOG	NOG146579
GeneTree	ENSGT00760000118784
HOGENOM	HOG000231307
HOVERGEN	HBG101120
InParanoid	P49651
KO	K04270
OMA	QFYYLPT
OrthoDB	EOG7GFB51
PhylomeDB	P49651
TreeFam	TF350009
Reactome	REACT_238852 REACT_257071 REACT_263374
NextBio	605927
PRO	PR:P49651
Proteomes	UP000002494
Genevestigator	P49651
GO	GO:0016324 GO:0016323 GO:0044297 GO:0030425 GO:0016021 GO:0097481 GO:0005886 GO:0045211 GO:0031686 GO:0043531 GO:0045032 GO:0005524 GO:0045031 GO:0045028 GO:0046982 GO:0097110 GO:0001973 GO:0007193 GO:0007568 GO:0042755 GO:0035589 GO:0007186 GO:0008347 GO:0051100 GO:0010700 GO:0030168 GO:0007204 GO:0051482 GO:0070374 GO:0046887 GO:0032962 GO:0043270 GO:0060406 GO:0001934 GO:0045944 GO:0072659 GO:0010469 GO:0042312 GO:0090075 GO:0070848 GO:0009612 GO:0019233 GO:0023019 GO:0042060
InterPro	IPR000276 IPR017452 IPR000142
PANTHER	PTHR24231:SF2
Pfam	PF00001
PRINTS	PR00237 PR00595
PROSITE	PS00237 PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
NOT\|involved_in	GO:0001774	microglial cell activation	PMID:11245682^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P47900	C		Seeded From UniProt	complete
involved_in	GO:0071415	cellular response to purine-containing compound	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P47900	P		Seeded From UniProt	complete
involved_in	GO:0008360	regulation of cell shape	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P47900	P		Seeded From UniProt	complete
involved_in	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P47900	P		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000956)	Seeded From UniProt	complete
enables	GO:0097110	scaffold protein binding	PMID:20847060^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P31016	F	occurs_in:(UBERON:0000956)	Seeded From UniProt	complete
involved_in	GO:0072659	protein localization to plasma membrane	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051100	negative regulation of binding	PMID:11390975^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	PMID:11390975^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P25099	F		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000956)	Seeded From UniProt	complete
enables	GO:0045032	ADP-activated adenosine receptor activity	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0045031	ATP-activated adenosine receptor activity	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_in:(CL:0002609)	Seeded From UniProt	complete
part_of	GO:0044297	cell body	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000956)	Seeded From UniProt	complete
part_of	GO:0044297	cell body	PMID:12417330^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002609)	Seeded From UniProt	complete
involved_in	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	PMID:11390975^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0031686	A1 adenosine receptor binding	PMID:11390975^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P25099	F		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0000956)	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:12417330^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0023019	signal transduction involved in regulation of gene expression	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0000956)	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	PMID:11390975^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	PMID:11390975^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0001973	adenosine receptor signaling pathway	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	PMID:20847060^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000300	regulation of synaptic vesicle exocytosis	PMID:16000618^[5]	ECO:0006062	wide-field fluorescence microscopy evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:2000300	regulation of synaptic vesicle exocytosis	PMID:16000618^[5]	ECO:0006054	pharmacological assay evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:2000300	regulation of synaptic vesicle exocytosis	PMID:16000618^[5]	ECO:0006042	cell fractionation evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:2000300	regulation of synaptic vesicle exocytosis	PMID:16000618^[5]	ECO:0000279	western blot evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	PMID:16000618^[5]	ECO:0006062	wide-field fluorescence microscopy evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	PMID:16000618^[5]	ECO:0006054	pharmacological assay evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	PMID:16000618^[5]	ECO:0006042	cell fractionation evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	PMID:16000618^[5]	ECO:0000279	western blot evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0099059	integral component of presynaptic active zone membrane	PMID:16000618^[5]	ECO:0006042	cell fractionation evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0099059	integral component of presynaptic active zone membrane	PMID:16000618^[5]	ECO:0000279	western blot evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:16000618^[5]	ECO:0006062	wide-field fluorescence microscopy evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:16000618^[5]	ECO:0006054	pharmacological assay evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:16000618^[5]	ECO:0006042	cell fractionation evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:16000618^[5]	ECO:0000279	western blot evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0097746	regulation of blood vessel diameter	PMID:12730558^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070848	response to growth factor	PMID:14714568^[7]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060406	positive regulation of penile erection	PMID:19303093^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0046887	positive regulation of hormone secretion	PMID:19515986^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	PMID:15152027^[10]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043531	ADP binding	PMID:15152027^[10]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0042755	eating behavior	PMID:17067301^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042060	wound healing	PMID:14714568^[7]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019233	sensory perception of pain	PMID:15740803^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	PMID:11557527^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	PMID:11557527^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010700	negative regulation of norepinephrine secretion	PMID:19447154^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009612	response to mechanical stimulus	PMID:14689471^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008347	glial cell migration	PMID:20681951^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007568	aging	PMID:11738148^[17]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	PMID:19373936^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	PMID:15152027^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
colocalizes_with	GO:0005739	mitochondrion	PMID:17292801^[19]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	PMID:11557527^[13]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0071415	cellular response to purine-containing compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P47900 ensembl:ENSP00000304767	P		Seeded From UniProt	complete
enables	GO:0045032	ADP-activated adenosine receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P47900 ensembl:ENSP00000304767	F		Seeded From UniProt	complete
involved_in	GO:0008360	regulation of cell shape	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P47900 ensembl:ENSP00000304767	P		Seeded From UniProt	complete
involved_in	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P47900 ensembl:ENSP00000304767	P		Seeded From UniProt	complete
part_of	GO:0005929	cilium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P47900 ensembl:ENSP00000304767	C		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P47900 ensembl:ENSP00000304767	C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P47900 ensembl:ENSP00000304767	F		Seeded From UniProt	complete
involved_in	GO:0071407	cellular response to organic cyclic compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49650 ensembl:ENSMUSP00000029331	P		Seeded From UniProt	complete
involved_in	GO:0043270	positive regulation of ion transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49650 ensembl:ENSMUSP00000029331	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49650 ensembl:ENSMUSP00000029331	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	P		Seeded From UniProt	complete
involved_in	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000142	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000142 InterPro:IPR000276 InterPro:IPR017452	C		Seeded From UniProt	complete
involved_in	GO:0030168	platelet activation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000142	P		Seeded From UniProt	complete
enables	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000142	F		Seeded From UniProt	complete
involved_in	GO:0090075	relaxation of muscle	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000142	P		Seeded From UniProt	complete
involved_in	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	PMID:20847060^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	PMID:11959647^[20]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Honda, S et al. (2001) Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J. Neurosci. 21 1975-82 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 Siow, NL et al. (2010) ATP induces synaptic gene expressions in cortical neurons: transduction and transcription control via P2Y1 receptors. Mol. Pharmacol. 78 1059-71 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Yoshioka, K et al. (2001) Heteromeric association creates a P2Y-like adenosine receptor. Proc. Natl. Acad. Sci. U.S.A. 98 7617-22 PubMed GONUTS page
↑ ^4.0 ^4.1 Yoshioka, K et al. (2002) Hetero-oligomerization of adenosine A1 receptors with P2Y1 receptors in rat brains. FEBS Lett. 531 299-303 PubMed GONUTS page
↑ ^5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 ^5.12 ^5.13 Rodrigues, RJ et al. (2005) Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J. Neurosci. 25 6286-95 PubMed GONUTS page
↑ Horiuchi, T et al. (2003) Comparison of P2 receptor subtypes producing dilation in rat intracerebral arterioles. Stroke 34 1473-8 PubMed GONUTS page
↑ ^7.0 ^7.1 Greig, AV et al. (2003) Purinergic receptor expression in the regeneration epidermis in a rat model of normal and delayed wound healing. Exp. Dermatol. 12 860-71 PubMed GONUTS page
↑ Gur, S et al. (2009) Management of erectile function by penile purinergic p2 receptors in the diabetic rat. J. Urol. 181 2375-82 PubMed GONUTS page
↑ Song, Z et al. (2009) Role of purinergic P2Y1 receptors in regulation of vasopressin and oxytocin secretion. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297 R478-84 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 Dixon, CJ et al. (2004) Regulation of rat hepatocyte function by P2Y receptors: focus on control of glycogen phosphorylase and cyclic AMP by 2-methylthioadenosine 5'-diphosphate. J. Pharmacol. Exp. Ther. 311 334-41 PubMed GONUTS page
↑ Kittner, H et al. (2006) Enhanced food intake after stimulation of hypothalamic P2Y1 receptors in rats: modulation of feeding behaviour by extracellular nucleotides. Eur. J. Neurosci. 24 2049-56 PubMed GONUTS page
↑ Yajima, H et al. (2005) Inhibitory, facilitatory, and excitatory effects of ATP and purinergic receptor agonists on the activity of rat cutaneous nociceptors in vitro. Neurosci. Res. 51 405-16 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 Dranoff, JA et al. (2001) Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia. Am. J. Physiol. Gastrointest. Liver Physiol. 281 G1059-67 PubMed GONUTS page
↑ Quintas, C et al. (2009) The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues. Neurochem. Int. 55 505-13 PubMed GONUTS page
↑ Christofi, FL et al. (2004) Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors. J. Comp. Neurol. 469 16-36 PubMed GONUTS page
↑ De Simone, R et al. (2010) TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression. J. Neurochem. 115 450-9 PubMed GONUTS page
↑ Miao, LY et al. (2001) Age-related changes in P2 receptor mRNA of rat cerebral arteries. Exp. Gerontol. 37 67-79 PubMed GONUTS page
↑ Wurm, A et al. (2009) Expression and function of P2Y receptors on Müller cells of the postnatal rat retina. Glia 57 1680-90 PubMed GONUTS page
↑ Krzeminski, P et al. (2007) Mitochondrial localization of P2Y1, P2Y2 and P2Y12 receptors in rat astrocytes and glioma C6 cells. Brain Res. Bull. 71 587-92 PubMed GONUTS page
↑ Ninomiya, H et al. (2002) Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart. Am. J. Physiol. Heart Circ. Physiol. 282 H1810-20 PubMed GONUTS page

[PMID:11245682-1] Honda, S et al. (2001) Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J. Neurosci. 21 1975-82 PubMed GONUTS page

[PMID:20847060-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 Siow, NL et al. (2010) ATP induces synaptic gene expressions in cortical neurons: transduction and transcription control via P2Y1 receptors. Mol. Pharmacol. 78 1059-71 PubMed GONUTS page

[PMID:11390975-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Yoshioka, K et al. (2001) Heteromeric association creates a P2Y-like adenosine receptor. Proc. Natl. Acad. Sci. U.S.A. 98 7617-22 PubMed GONUTS page

[PMID:12417330-4] 4.0 ^4.1 Yoshioka, K et al. (2002) Hetero-oligomerization of adenosine A1 receptors with P2Y1 receptors in rat brains. FEBS Lett. 531 299-303 PubMed GONUTS page

[PMID:16000618-5] 5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 ^5.12 ^5.13 Rodrigues, RJ et al. (2005) Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J. Neurosci. 25 6286-95 PubMed GONUTS page

[PMID:12730558-6] Horiuchi, T et al. (2003) Comparison of P2 receptor subtypes producing dilation in rat intracerebral arterioles. Stroke 34 1473-8 PubMed GONUTS page

[PMID:14714568-7] 7.0 ^7.1 Greig, AV et al. (2003) Purinergic receptor expression in the regeneration epidermis in a rat model of normal and delayed wound healing. Exp. Dermatol. 12 860-71 PubMed GONUTS page

[PMID:19303093-8] Gur, S et al. (2009) Management of erectile function by penile purinergic p2 receptors in the diabetic rat. J. Urol. 181 2375-82 PubMed GONUTS page

[PMID:19515986-9] Song, Z et al. (2009) Role of purinergic P2Y1 receptors in regulation of vasopressin and oxytocin secretion. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297 R478-84 PubMed GONUTS page

[PMID:15152027-10] 10.0 ^10.1 ^10.2 Dixon, CJ et al. (2004) Regulation of rat hepatocyte function by P2Y receptors: focus on control of glycogen phosphorylase and cyclic AMP by 2-methylthioadenosine 5'-diphosphate. J. Pharmacol. Exp. Ther. 311 334-41 PubMed GONUTS page

[PMID:17067301-11] Kittner, H et al. (2006) Enhanced food intake after stimulation of hypothalamic P2Y1 receptors in rats: modulation of feeding behaviour by extracellular nucleotides. Eur. J. Neurosci. 24 2049-56 PubMed GONUTS page

[PMID:15740803-12] Yajima, H et al. (2005) Inhibitory, facilitatory, and excitatory effects of ATP and purinergic receptor agonists on the activity of rat cutaneous nociceptors in vitro. Neurosci. Res. 51 405-16 PubMed GONUTS page

[PMID:11557527-13] 13.0 ^13.1 ^13.2 Dranoff, JA et al. (2001) Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia. Am. J. Physiol. Gastrointest. Liver Physiol. 281 G1059-67 PubMed GONUTS page

[PMID:19447154-14] Quintas, C et al. (2009) The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues. Neurochem. Int. 55 505-13 PubMed GONUTS page

[PMID:14689471-15] Christofi, FL et al. (2004) Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors. J. Comp. Neurol. 469 16-36 PubMed GONUTS page

[PMID:20681951-16] De Simone, R et al. (2010) TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression. J. Neurochem. 115 450-9 PubMed GONUTS page

[PMID:11738148-17] Miao, LY et al. (2001) Age-related changes in P2 receptor mRNA of rat cerebral arteries. Exp. Gerontol. 37 67-79 PubMed GONUTS page

[PMID:19373936-18] Wurm, A et al. (2009) Expression and function of P2Y receptors on Müller cells of the postnatal rat retina. Glia 57 1680-90 PubMed GONUTS page

[PMID:17292801-19] Krzeminski, P et al. (2007) Mitochondrial localization of P2Y1, P2Y2 and P2Y12 receptors in rat astrocytes and glioma C6 cells. Brain Res. Bull. 71 587-92 PubMed GONUTS page

[PMID:11959647-20] Ninomiya, H et al. (2002) Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart. Am. J. Physiol. Heart Circ. Physiol. 282 H1810-20 PubMed GONUTS page

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