RAT:ID1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Id1 (synonyms: Id-1)
Protein Name(s)	DNA-binding protein inhibitor ID-1 Inhibitor of DNA binding 1 Inhibitor of differentiation 1
External Links
UniProt	P41135
EMBL	L23148 D10862 M86708
PIR	A53334 JC2111
RefSeq	NP_036929.2
UniGene	Rn.2113
ProteinModelPortal	P41135
BioGrid	247301
IntAct	P41135
STRING	10116.ENSRNOP00000052261
PaxDb	P41135
PRIDE	P41135
Ensembl	ENSRNOT00000029660
GeneID	25261
KEGG	rno:25261
UCSC	RGD:2858
CTD	3397
RGD	2858
eggNOG	ENOG410IWDR ENOG4111VAY
GeneTree	ENSGT00390000000908
HOGENOM	HOG000234788
HOVERGEN	HBG009009
InParanoid	P41135
KO	K04680
OMA	YIWDLEL
OrthoDB	EOG7X9G8G
PhylomeDB	P41135
TreeFam	TF326217
Reactome	R-RNO-2559585
NextBio	605911
PRO	PR:P41135
Proteomes	UP000002494
ExpressionAtlas	P41135
Genevisible	P41135
GO	GO:0005813 GO:0005794 GO:0005654 GO:0005634 GO:0070628 GO:0008022 GO:0042803 GO:0047485 GO:0003700 GO:0008134 GO:0030509 GO:0007420 GO:0036164 GO:1903351 GO:0071364 GO:1990090 GO:1901653 GO:0071560 GO:0007623 GO:0032963 GO:0001886 GO:0007507 GO:0060425 GO:0060426 GO:0043066 GO:0050774 GO:0045602 GO:0045668 GO:0032091 GO:1903026 GO:0043433 GO:0000122 GO:0045892 GO:0030182 GO:0032233 GO:0050679 GO:0010628 GO:0031648 GO:0045765 GO:0043408 GO:1901342 GO:0046677 GO:0014070 GO:0006351
Gene3D	4.10.280.10
InterPro	IPR011598 IPR026052
PANTHER	PTHR11723
Pfam	PF00010
SMART	SM00353
SUPFAM	SSF47459
PROSITE	PS50888

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0120163	negative regulation of cold-induced thermogenesis	PMID:28270523^[1]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20067	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P20067	P	Seeded From UniProt	complete
involved_in	GO:1990090	cellular response to nerve growth factor stimulus	PMID:7623812^[2]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:1903351	cellular response to dopamine	PMID:20600660^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:1901653	cellular response to peptide	PMID:16706836^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:1901342	regulation of vasculature development	PMID:21472453^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0071560	cellular response to transforming growth factor beta stimulus	PMID:16628634^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0071364	cellular response to epidermal growth factor stimulus	PMID:7623812^[2]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0070628	proteasome binding	PMID:23831032^[7]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:621109	F	Seeded From UniProt	complete
involved_in	GO:0050774	negative regulation of dendrite morphogenesis	PMID:19167333^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	PMID:23335245^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0047485	protein N-terminus binding	PMID:23831032^[7]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:734298	F	Seeded From UniProt	complete
involved_in	GO:0045602	negative regulation of endothelial cell differentiation	PMID:20830586^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0043392	negative regulation of DNA binding	PMID:7623812^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	PMID:19137015^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:8106493^[12]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0036164	cell-abiotic substrate adhesion	PMID:11600477^[13]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032233	positive regulation of actin filament bundle assembly	PMID:16628634^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032091	negative regulation of protein binding	PMID:23831032^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:7908517^[14]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	PMID:20600660^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:23335245^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:8106493^[12]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:1332500	F	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:7623812^[2]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:620914	F	Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	PMID:8106493^[12]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:9814817^[15]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005813	centrosome	PMID:19167333^[8]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16628634^[6]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:23831032^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051726	regulation of cell cycle	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000919548 RGD:2860	P	Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96397 MGI:MGI:99414 PANTHER:PTN000919548 UniProtKB:O73933 UniProtKB:Q90X14 UniProtKB:Q90X15	P	Seeded From UniProt	complete
involved_in	GO:0043392	negative regulation of DNA binding	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000575 MGI:MGI:96396 MGI:MGI:96397 PANTHER:PTN000919548	P	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000919548 RGD:2858 RGD:2859 RGD:2860	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96398 PANTHER:PTN000919548 RGD:2858	F	Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548	P	Seeded From UniProt	complete
colocalizes_with	GO:0005737	cytoplasm	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548 RGD:2859 UniProtKB:Q02363	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000575 MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548 RGD:2858 RGD:2859 RGD:2860 UniProtKB:O73933 UniProtKB:P47928 UniProtKB:Q02363	C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96398 PANTHER:PTN000919548	F	Seeded From UniProt	complete
enables	GO:0001085	RNA polymerase II transcription factor binding	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99414 PANTHER:PTN000919548	F	Seeded From UniProt	complete
involved_in	GO:0120163	negative regulation of cold-induced thermogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0090074	negative regulation of protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0060426	lung vasculature development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0060425	lung morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0046677	response to antibiotic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0045765	regulation of angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0045668	negative regulation of osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
enables	GO:0043621	protein self-association	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	F	Seeded From UniProt	complete
involved_in	GO:0043408	regulation of MAPK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0043392	negative regulation of DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0032963	collagen metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0031648	protein destabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0030509	BMP signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0006351	transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	F	Seeded From UniProt	complete
involved_in	GO:0001886	endothelial cell morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20067 ensembl:ENSMUSP00000092019	P	Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	P	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	C	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	C	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	P	Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011598 InterPro:IPR036638	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Patil, M et al. (2017) Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning. Diabetes 66 1611-1625 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Einarson, MB & Chao, MV (1995) Regulation of Id1 and its association with basic helix-loop-helix proteins during nerve growth factor-induced differentiation of PC12 cells. Mol. Cell. Biol. 15 4175-83 PubMed GONUTS page
↑ ^3.0 ^3.1 Konishi, H et al. (2010) Id1, Id2 and Id3 are induced in rat melanotrophs of the pituitary gland by dopamine suppression under continuous stress. Neuroscience 169 1527-34 PubMed GONUTS page
↑ Persson, AI et al. (2006) Requirement for Id1 in opioid-induced oligodendrogenesis in cultured adult rat hippocampal progenitors. Eur. J. Neurosci. 23 2277-88 PubMed GONUTS page
↑ Belmokhtar, K et al. (2011) Regeneration of three layers vascular wall by using BMP2-treated MSC involving HIF-1α and Id1 expressions through JAK/STAT pathways. Stem Cell Rev 7 847-59 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Wiercinska, E et al. (2006) Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells. Hepatology 43 1032-41 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 Puram, SV et al. (2013) The ubiquitin receptor S5a/Rpn10 links centrosomal proteasomes with dendrite development in the mammalian brain. Cell Rep 4 19-30 PubMed GONUTS page
↑ ^8.0 ^8.1 Kim, AH et al. (2009) A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell 136 322-36 PubMed GONUTS page
↑ ^9.0 ^9.1 Chen, J et al. (2013) Bone morphogenetic protein 4, inhibitor of differentiation 1, and epidermal growth factor receptor regulate the survival of cochlear sensory epithelial cells. J. Neurosci. Res. 91 515-26 PubMed GONUTS page
↑ Yu, Y et al. (2010) CCN1 promotes the differentiation of endothelial progenitor cells and reendothelialization in the early phase after vascular injury. Basic Res. Cardiol. 105 713-24 PubMed GONUTS page
↑ Cao, Y et al. (2009) TGF-beta repression of Id2 induces apoptosis in gut epithelial cells. Oncogene 28 1089-98 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 Springhorn, JP et al. (1994) Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization. J. Biol. Chem. 269 5132-6 PubMed GONUTS page
↑ Vincent, KJ et al. (2001) Regulation of E-box DNA binding during in vivo and in vitro activation of rat and human hepatic stellate cells. Gut 49 713-9 PubMed GONUTS page
↑ Nagata, Y & Todokoro, K (1994) Activation of helix-loop-helix proteins Id1, Id2 and Id3 during neural differentiation. Biochem. Biophys. Res. Commun. 199 1355-62 PubMed GONUTS page
↑ Tzeng, SF & de Vellis, J (1998) Id1, Id2, and Id3 gene expression in neural cells during development. Glia 24 372-81 PubMed GONUTS page
↑ ^16.0 ^16.1 ^16.2 ^16.3 ^16.4 ^16.5 ^16.6 ^16.7 ^16.8 ^16.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:28270523-1] Patil, M et al. (2017) Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning. Diabetes 66 1611-1625 PubMed GONUTS page

[PMID:7623812-2] 2.0 ^2.1 ^2.2 ^2.3 Einarson, MB & Chao, MV (1995) Regulation of Id1 and its association with basic helix-loop-helix proteins during nerve growth factor-induced differentiation of PC12 cells. Mol. Cell. Biol. 15 4175-83 PubMed GONUTS page

[PMID:20600660-3] 3.0 ^3.1 Konishi, H et al. (2010) Id1, Id2 and Id3 are induced in rat melanotrophs of the pituitary gland by dopamine suppression under continuous stress. Neuroscience 169 1527-34 PubMed GONUTS page

[PMID:16706836-4] Persson, AI et al. (2006) Requirement for Id1 in opioid-induced oligodendrogenesis in cultured adult rat hippocampal progenitors. Eur. J. Neurosci. 23 2277-88 PubMed GONUTS page

[PMID:21472453-5] Belmokhtar, K et al. (2011) Regeneration of three layers vascular wall by using BMP2-treated MSC involving HIF-1α and Id1 expressions through JAK/STAT pathways. Stem Cell Rev 7 847-59 PubMed GONUTS page

[PMID:16628634-6] 6.0 ^6.1 ^6.2 Wiercinska, E et al. (2006) Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells. Hepatology 43 1032-41 PubMed GONUTS page

[PMID:23831032-7] 7.0 ^7.1 ^7.2 ^7.3 Puram, SV et al. (2013) The ubiquitin receptor S5a/Rpn10 links centrosomal proteasomes with dendrite development in the mammalian brain. Cell Rep 4 19-30 PubMed GONUTS page

[PMID:19167333-8] 8.0 ^8.1 Kim, AH et al. (2009) A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell 136 322-36 PubMed GONUTS page

[PMID:23335245-9] 9.0 ^9.1 Chen, J et al. (2013) Bone morphogenetic protein 4, inhibitor of differentiation 1, and epidermal growth factor receptor regulate the survival of cochlear sensory epithelial cells. J. Neurosci. Res. 91 515-26 PubMed GONUTS page

[PMID:20830586-10] Yu, Y et al. (2010) CCN1 promotes the differentiation of endothelial progenitor cells and reendothelialization in the early phase after vascular injury. Basic Res. Cardiol. 105 713-24 PubMed GONUTS page

[PMID:19137015-11] Cao, Y et al. (2009) TGF-beta repression of Id2 induces apoptosis in gut epithelial cells. Oncogene 28 1089-98 PubMed GONUTS page

[PMID:8106493-12] 12.0 ^12.1 ^12.2 Springhorn, JP et al. (1994) Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization. J. Biol. Chem. 269 5132-6 PubMed GONUTS page

[PMID:11600477-13] Vincent, KJ et al. (2001) Regulation of E-box DNA binding during in vivo and in vitro activation of rat and human hepatic stellate cells. Gut 49 713-9 PubMed GONUTS page

[PMID:7908517-14] Nagata, Y & Todokoro, K (1994) Activation of helix-loop-helix proteins Id1, Id2 and Id3 during neural differentiation. Biochem. Biophys. Res. Commun. 199 1355-62 PubMed GONUTS page

[PMID:9814817-15] Tzeng, SF & de Vellis, J (1998) Id1, Id2, and Id3 gene expression in neural cells during development. Glia 24 372-81 PubMed GONUTS page

[PMID:21873635-16] 16.0 ^16.1 ^16.2 ^16.3 ^16.4 ^16.5 ^16.6 ^16.7 ^16.8 ^16.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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RAT:ID1

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