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RAT:FEV

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Fev (synonyms: Pet1)
Protein Name(s) Protein FEV

PC12 ETS domain-containing transcription factor 1 PC12 ETS factor 1 Pet-1

External Links
UniProt O70132
EMBL U91679
RefSeq NP_653354.2
UniGene Rn.83616
ProteinModelPortal O70132
SMR O70132
STRING 10116.ENSRNOP00000024190
PaxDb O70132
Ensembl ENSRNOT00000024190
GeneID 246271
KEGG rno:246271
UCSC RGD:628860
CTD 54738
RGD 628860
eggNOG NOG287001
GeneTree ENSGT00760000118907
HOGENOM HOG000234879
HOVERGEN HBG095796
InParanoid O70132
KO K09437
OMA LMFNMYL
OrthoDB EOG73V6K8
PhylomeDB O70132
TreeFam TF316214
NextBio 623637
PRO PR:O70132
Proteomes UP000002494
Genevestigator O70132
GO GO:0005634
GO:0003690
GO:0043565
GO:0000981
GO:0003700
GO:0030154
GO:0048665
GO:0042551
GO:0045893
GO:0006357
GO:0006366
Gene3D 1.10.10.10
InterPro IPR000418
IPR011991
Pfam PF00178
PRINTS PR00454
SMART SM00413
PROSITE PS00345
PS00346
PS50061

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050331

thiamin diphosphate kinase activity

PMID:21049048[1]

ECO:0000269

F

Table 8 shows ThTp levels related to this protein. Also Figure 1 describes the kinase activity.

complete

GO:0006757

ADP phosphorylation

PMID:21049048[1]

ECO:0000269

P

Table 8 shows AThDP levels related to this protein. Also Figure 1 illustrates how AThDP and ATP are created by ADP phosphorylation.

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001952)

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001952)

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003690

double-stranded DNA binding

PMID:9468386[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109336
PANTHER:PTN000218930

P

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95455
MGI:MGI:95610
MGI:MGI:98282
PANTHER:PTN000218930
UniProtKB:Q15723

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000097
FB:FBgn0000567
FB:FBgn0003118
MGI:MGI:101762
MGI:MGI:107180
MGI:MGI:109637
MGI:MGI:1335079
MGI:MGI:1353422
MGI:MGI:2449712
MGI:MGI:95455
MGI:MGI:95554
MGI:MGI:95610
MGI:MGI:98282
MGI:MGI:99423
PANTHER:PTN000218930
RGD:1359607
RGD:1598663
RGD:2583
UniProtKB:P14921
UniProtKB:P17947
UniProtKB:P19419
UniProtKB:P32519
UniProtKB:P41161
UniProtKB:Q01543
UniProtKB:Q06546
WB:WBGene00002990
WB:WBGene00017687

C

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000218930
UniProtKB:Q15723

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000418

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000418

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000418

F

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gangolf, M et al. (2010) Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells. PLoS ONE 5 e13616 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Fyodorov, D et al. (1998) Pet-1, a novel ETS domain factor that can activate neuronal nAchR gene transcription. J. Neurobiol. 34 151-63 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page