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RAT:APBA1
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Apba1 (synonyms: Mint1, X11) | |
| Protein Name(s) | Amyloid beta A4 precursor protein-binding family A member 1
Adapter protein X11alpha Neuron-specific X11 protein Neuronal Munc18-1-interacting protein 1 Mint-1 | |
| External Links | ||
| UniProt | O35430 | |
| EMBL | AF029105 | |
| RefSeq | NP_113967.1 | |
| UniGene | Rn.54819 | |
| PDB | 4DBB | |
| PDBsum | 4DBB | |
| ProteinModelPortal | O35430 | |
| SMR | O35430 | |
| BioGrid | 249774 | |
| IntAct | O35430 | |
| MINT | MINT-102360 | |
| STRING | 10116.ENSRNOP00000020123 | |
| BindingDB | O35430 | |
| PhosphoSite | O35430 | |
| PaxDb | O35430 | |
| PRIDE | O35430 | |
| GeneID | 83589 | |
| KEGG | rno:83589 | |
| UCSC | RGD:620844 | |
| CTD | 320 | |
| RGD | 620844 | |
| eggNOG | NOG283022 | |
| HOGENOM | HOG000033981 | |
| HOVERGEN | HBG050523 | |
| InParanoid | O35430 | |
| KO | K04531 | |
| PhylomeDB | O35430 | |
| NextBio | 616139 | |
| PRO | PR:O35430 | |
| Proteomes | UP000002494 | |
| ExpressionAtlas | O35430 | |
| Genevestigator | O35430 | |
| GO | GO:0005794 GO:0005634 GO:0048471 GO:0005886 GO:0043234 GO:0001540 GO:0030165 GO:0005546 GO:0032403 GO:0014051 GO:0014047 GO:0001701 GO:0006886 GO:0007626 GO:0035264 GO:0010468 GO:0016079 | |
| Gene3D | 2.30.29.30 2.30.42.10 | |
| InterPro | IPR001478 IPR011993 IPR006020 | |
| Pfam | PF00595 PF00640 | |
| SMART | SM00228 SM00462 | |
| SUPFAM | SSF50156 | |
| PROSITE | PS50106 PS01179 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0043197 |
dendritic spine |
ECO:0000314 |
C |
Figure 3, panel A shows GFP-tagged X11-alpha localized at dendritic spines. Panels B-D show movement of GFP-X11-alpha into dendritic spines. |
complete | |||||
| GO:0043198 |
dendritic shaft |
ECO:0000314 |
C |
Figure 3, panel A shows GFP-tagged X11-alpha localized at dendritic spines. Panels B-D show movement of GFP-X11-alpha into dendritic spines. |
complete | |||||
|
part_of |
GO:0043197 |
dendritic spine |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030165 |
PDZ domain binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
RGD:621660 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005546 |
phosphatidylinositol-4,5-bisphosphate binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001540 |
amyloid-beta binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
RGD:736021 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0045202 |
synapse |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000960968 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043197 |
dendritic spine |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000960968 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007268 |
chemical synaptic transmission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1261791 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0026313 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0026313 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0001540 |
amyloid-beta binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000269512 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0001540 |
amyloid-beta binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007268 |
chemical synaptic transmission |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0008021 |
synaptic vesicle |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0065003 |
protein-containing complex assembly |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016079 |
synaptic vesicle exocytosis |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-RNO-6794339 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Jones, KA et al. (2014) Scaffold protein X11α interacts with kalirin-7 in dendrites and recruits it to Golgi outposts. J. Biol. Chem. 289 35517-29 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Okamoto, M & Südhof, TC (1997) Mints, Munc18-interacting proteins in synaptic vesicle exocytosis. J. Biol. Chem. 272 31459-64 PubMed GONUTS page
- ↑ Leonoudakis, D et al. (2004) Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. J. Biol. Chem. 279 22331-46 PubMed GONUTS page
- ↑ Biederer, T et al. (2002) Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms. J. Neurosci. 22 7340-51 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
c
p
- GO:0030165 ! PDZ domain binding
- GO:0048471 ! perinuclear region of cytoplasm
- GO:0005546 ! phosphatidylinositol-4,5-bisphosphate binding
- GO:0005886 ! plasma membrane
- GO:0065003 ! protein-containing complex assembly
- GO:0032991 ! protein-containing complex
- GO:0044877 ! protein-containing complex binding
- GO:0015031 ! protein transport
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