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MYCLE:GYRA
Contents
| Species (Taxon ID) | Mycobacterium leprae (strain TN). (272631) | |
| Gene Name(s) | gyrA (ECO:0000255 with HAMAP-Rule:MF_01897) | |
| Protein Name(s) | DNA gyrase subunit A (ECO:0000255 with HAMAP-Rule:MF_01897)
Mle gyrA intein | |
| External Links | ||
| UniProt | Q57532 | |
| EMBL | Z70722 Z68206 AL583917 X87124 | |
| PIR | F86909 T10006 | |
| RefSeq | NP_301134.1 | |
| ProteinModelPortal | Q57532 | |
| SMR | Q57532 | |
| STRING | 272631.ML0006 | |
| MEROPS | N10.001 | |
| EnsemblBacteria | CAC29514 | |
| GeneID | 908154 | |
| KEGG | mle:ML0006 | |
| PATRIC | 18050092 | |
| Leproma | ML0006 | |
| eggNOG | COG1372 | |
| HOGENOM | HOG000076278 | |
| KO | K02469 | |
| OrthoDB | EOG661H5V | |
| Proteomes | UP000000806 | |
| GO | GO:0005694 GO:0005737 GO:0005524 GO:0003677 GO:0003918 GO:0004519 GO:0006265 GO:0006261 GO:0016539 | |
| Gene3D | 1.10.268.10 2.170.16.10 3.10.28.10 3.30.1360.40 3.90.199.10 | |
| HAMAP | MF_01897 | |
| InterPro | IPR024946 IPR005743 IPR006691 IPR028992 IPR003586 IPR003587 IPR027434 IPR006142 IPR004042 IPR006141 IPR002205 IPR013758 IPR013757 IPR013760 | |
| Pfam | PF03989 PF00521 PF14528 | |
| PRINTS | PR00379 | |
| SMART | SM00305 SM00306 SM00434 | |
| SUPFAM | SSF51294 SSF55608 SSF56719 | |
| TIGRFAMs | TIGR01063 TIGR01443 TIGR01445 | |
| PROSITE | PS50818 PS50819 PS50817 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0034335 |
DNA supercoiling activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002205 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003916 |
DNA topoisomerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003918 |
DNA topoisomerase type II (ATP-hydrolyzing) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002205 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004519 |
endonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002205 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005694 |
chromosome |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006259 |
DNA metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006265 |
DNA topological change |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016539 |
intein-mediated protein splicing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003916 |
DNA topoisomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Matrat, S et al. (2007) Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones. Antimicrob. Agents Chemother. 51 1643-8 PubMed GONUTS page